SOVREMENNAYA PEDIATRIYA.2018.7(95):51-58; doi 10.15574/SP.2018.95.51

Дорош О. І., Дудаш П. Й., Петрончак О. А., Масинник Ю. С., Селезньов О. О., Щуровський О. М., Киричук І. В., Мелько І. П.
Комунальне некомерційне підприємство Львівської обласної ради «Західноукраїнський спеціалізований дитячий медичний центр», Україна
Комунальний заклад Львівської обласної ради «Львівське обласне патологоанатомічне бюро», Україна
Центр медичних іновацій NOVO, м. Львів, Україна
Комунальна 4-та міська клінічна лікарня, м. Львів, Україна
Патоморфологічна лабораторія «CSD Health Care», м. Київ, Україна

Хвороба Горема (Gorham—Stout disease (GSD) — це рідкісне захворювання невизначеної етіології, яке характеризується спонтанним і прогресуючим ідіопатичним масивним остеолізом однієї або декількох кісток скелету без кореляції зі статтю, расою, типом успадкування та географічного місця народження пацієнтів. У міжнародній літературі описано близько 200 випадків захворювання. Радіологічні зміни при GSD доволі специфічні, у деяких випадках можлива повна резорбція ураженої кістки з ознаками так званої «фантомної кістки» або зникнення кісток. Метою повідомлення є ознайомлення медичної спільноти з цим рідкісним захворюванням та обговорення гістологічної й клінічної презентації хвороби Горема з ураженням грудного та поперекового відділу хребта, ребер, із двобічним гідротораксом, особливостями радіологічних знахідок із коротким оглядом літератури.

Ключові слова: Gorham—Stout disease, остеолізіс, гемангіоматоз, хвороби кісток, діти, рідкісні хвороби.

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Стаття надійшла до редакції 12.05.2018 р., прийнята до друку 15.11.2018 р.