Ukrainian Journal of Perinatology and Pediatrics. 2025.1(101): 143-151. doi: 10.15574/PP.2025.1(101).143151
Karlova O. O.^1,2, Kyrylchuk O. O.^1,2, Halishyna H. O.^2
1Shupyk National University of Health of Ukraine, Kyiv
²Specialized Mammology Center of PC "First Private Clinic", Kyiv, Ukraine

For citation: Karlova OO, Kyrylchuk OO, Halishyna HO. (2025). Complex sclerosing lesions of the mammary gland: clinical cases, diagnostic aspects. Ukrainian Journal of Perinatology and Pediatrics. 1(101): 143-151. doi: 10.15574/PP.2025.1(101).143151.
Article received: Dec 03, 2024. Accepted for publication: Mar 15, 2025.

Aim – to clarify the clinical and diagnostic aspects of breast diseases in the clinical examination of patients
The study included 83 workers who were examined at the mammology centre in Kyiv. The average age of the examined 48.7±2.8. All patients underwent a comprehensive examination of the mammary glands, which included a general clinical examination, ultrasound, mammographic examination of the mammary glands, and, if necessary, morphological verification.
Clinical cases. The obtained analysis of clinical cases demonstrated: In 38% of patients, diagnosis was based on a complaint of a palpable mass in the breast, 11% of patients had pain, 51% were referred by their attending physicians for a routine breast examination.  The lesions had the following ultrasound features: hypoechoic mass, spiculation and contour angulation; colour Doppler mapping showed perinodular blood flow in 47% of cases and avascular in 53%. According to the BIRADS descriptive system, the ultrasound examination was classified as category 5 in 87% of cases and category 4 in 23%. The MMG examination resulted in a conclusion similar to category 2. In 81% of cases, the histological stratification corresponded to radial breast scar, in 19% to lobular DCIS. Patients were offered surgical treatment
Conclusions. Screening of breast diseases, in particular, complex sclerosing breast diseases, should include examination of patients with the use of general clinical, ultrasound and mammography examinations.
The research was carried out in accordance with the principles of the Helsinki Declaration. The informed consent of the patient was obtained for conducting the studies.
No conflict of interests was declared by the authors.
Keywords: complex sclerosing diseases, ultrasound examination, mammography.

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