Modern Pediatrics. Ukraine. (2026).1(153): 16-27. doi: 10.15574/SP.2026.1(153).1627
Hlushko K. T., Boyarchuk O. R.
I. Horbachevsky Ternopil National Medical University, Ukraine

For citation: Hlushko KT, Boyarchuk OR. (2026). Chronic constipation and incontinence in children with neurogenic bowel dysfunction: current management approaches (literature review). Modern Pediatrics. Ukraine. 1(153): 16-27. doi: 10.15574/SP.2026.1(153).1627.
Article received: Jul 21, 2025. Accepted for publication: Feb 08, 2026.

Neurogenic bowel dysfunction (NBD) in children with spinal cord lesions, particularly in those with spina bifida, represents a significant clinical problem that markedly affects quality of life, social integration, and long-term outcomes, requiring a multidisciplinary management approach.
Aim – to analyze and summarize current evidence on the pathophysiology, clinical manifestations, and management strategies of NBD in children.
This review summarizes current concepts of NBD pathophysiology, including impaired colonic innervation, altered motility, and sensory dysfunction leading to chronic constipation and fecal incontinence. The clinical presentation is described in relation to the level of neurological impairment. A stepwise management approach is presented, including dietary modifications and behavioral interventions, pharmacological treatment (osmotic and stimulant laxatives), rectal interventions (suppositories, microenemas, transanal irrigation), and surgical options in refractory cases. Particular attention is paid to the safety and long-term use of laxatives in pediatric patients. Current clinical guidelines for the management of children with NBD are reviewed, including recommendations from the Spina Bifida Association and other international bodies.
Conclusions. Neurogenic bowel dysfunction in children requires an individualized, stepwise approach based on age, level of neurological impairment, and clinical severity. Early implementation of comprehensive management strategies, including behavioral, pharmacological, and when necessary invasive interventions, improves symptom control and quality of life. Multidisciplinary care and adherence to current clinical guidelines are essential for optimal patient outcomes.
The authors declare no conflict of interest.
Keywords: neurogenic bowel dysfunction, children, spina bifida, constipation, encopresis.

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