HEALTH OF WOMAN. 2016.1(107):75–80 
 

Treatment of pregnant with the threat of premature births and thrombophilic disorders 
 

Zhuk S. I., Us I. V.

National Medical Academy of Postgraduate Education P. L. Shupyk, Kiev

Perinatal center, Kiev 
 

Purpose. To study the efficiency of correction of coagulation disorders in women with the threat of premature births of trombophilic genesis. 
 

Materials and methods. Treatment is conducted 66 women with the threat of premature births and thrombophilic disorders. Correction of coagulation disorders is developed with the use of geparinoid sulodeksid, low-molecular heparin of bemiparina sodium, antiagregant aspirin, folacin, vitamins of B and omega-3 fat acids dependency upon reason and character of expressed of the trombophilic state. For all pregnant studied the state of the system of hemostazis and state of fetus before and after treatment. 
 

Results. Use of the indicated therapy at 36 pregnant simultaneously with the standard chart of treatment of threat of premature births resulted in normalization of indexes of the system of hemostasis and improvement of the state of fetus: the amount of pathological cardiotocographic changes diminished, the general point of estimation of biophysical profile of fetus increased, dopplerometria research of blood stream in an umbilical cord specified on the decline of indexes of vascular resistance, that testified to indemnification of blood stream. 
 

Conclusion. Correction of coagulation allowed to attain more high-purity of timely births, reduce frequency of complications at new-born and improve perinatal results. 
 

Key words: thrombophilic disorders, threat of premature births, system of gemostazis, correction of coagulation disorders, D-dimer. 
 

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