PERINATOLOGIYA I PEDIATRIYA.2013.4(56):43–46; doi 10.15574/PP.2013.56.43

The significance of functional condition of digestive system in the course of atopic dermatitis in children

Banadyha N. V.

Ternopil State Medical University by I.Ya. Horbachevskyy, Ternopil, Ukraine

Objective. To examine the functional status of the digestive system in children with atopic dermatitis and to propose the methods of correction.

Patients and methods. Advanced integrated laboratory and instrumental investigations were conducted among 37 children with atopic dermatitis aged from 7 months to 4 years. The study of ethiological meaningful allergens by immune enzyme analysis with determination of specific IgE class antibodies to food, inhalant (pollen, household, epidermal) allergens took place. In order to examine the condition of the digestive system the biochemical blood tests, sonography of the abdomen, coprology analysis, determination of the level of total antibodies to giardia and ascaris were used.

Results. Among children with atopic dermatitis the dominant form was moderate (54.06%).The severe dermatitis was observed in patients aged 10 to 18 months. The prevalence of polyvalent sensitization was determined (more than 3) to foods in 75.67% of cases and in 13.51% of children — causative allergens were 5 or more. In 43.24% of patients the increased sensitization to inhalant allergens was diagnosed. The comprehensive survey of patients revealed a high prevalence of functional disorders of the digestive system: functional disorders of the gallbladder of the hypotonic type (56.70%), dysfunction of the sphincter of Odi by pancreatic type (54.05%), intestinal dysbiosis (67.57%), and and helminthiasis (ascariasis) and intestinal giardiasis. The correction of medical activities in atopic dermatitis requires the appointment of enzymes (panhrol) and differentiated adding of: probiotics, antihelmintic and antiparasitic drugs.

Conclusions. The high prevalence of functional condition of the digestive system in atopic dermatitis causes the expansion of the range of diagnostic activities and targeted correction of treatment.

Key words: children, digestive system, atopic dermatitis.

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