PERINATOLOGIYA I PEDIATRIYA. 2016.2(66):18-21; doi 10.15574/PP.2016.66.18 
 

The safety of use of selective beta-blockers during the pregnancy (experimental studies) 
 

Limanskaia A. Yu., Davydova Yu. V.

SI «Institute of Pediatrics, Obstetrics and Gynecology NAMS of Ukraine», Kiev 
 

The effect of «Biprolol» selective preparation on the tone and contractile activity of the myometrium of pregnant rats is examined. Experimental studies have shown that cardioselective agents such as «Biprolol» lower bind with β2-receptors and thereby not cause the tone of pregnant uterus. 
 

Key words: selective beta-blockers, pregnancy, experimental research. 
 

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