- The incidence of malignant neoplasms in children in the Republic of Azerbaijan in 2013 year
The incidence of malignant neoplasms in children in the Republic of Azerbaijan in 2013 year
SOVREMENNAYA PEDIATRIYA. 2014. 7(63):124–125; doi 10.15574/SP.2014.63.124
The incidence of malignant neoplasms in children in the Republic of Azerbaijan in 2013 year
Mardanly F. A., Isaev I. G., Nasirli A. A.
The aim of this work was to study the epidemiological situation regarding the incidence of malignant neoplasms in patients of the age group 0–17 years in the Republic of Azerbaijan in 2013 year. Studies have shown that malignant neoplasms in childhood are not a rare disease. Leading nosological form of both sexes are diseases of the lymphoid and hematopoietic tissues (60.0% and 52.0%). Extensive indicator in children was relatively low (1.4%). Standardized, regardless of age in boys was 1.4 times higher than in girls. The results of study confirm the need of further examination of the problem of pediatric oncology.
Key words: children, malignant neoplasm, extensive index, standardized measure.
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http://media-medexpert.com.ua/Modern%20Pediatry%202014/SP_07_2014/index.html#124/z
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SOVREMENNAYA PEDIATRIYA. 2014. 7(63):126–129; DOI 10.15574/SP.2014.63.126
Family case of nijmegen syndrome complicated by ebv; lymphoproliferative syndrome and lymphoma
Kostyuchenko L.
SOVREMENNAYA PEDIATRIYA. 2014. 7(63):126–129; doi 10.15574/SP.2014.63.126
Family case of nijmegen syndrome complicated by ebv; lymphoproliferative syndrome and lymphoma
Kostyuchenko L.
Nijmegen breakage syndrome (NBS) is a rare autosomal recessive condition of chromosomal instability that is clinically characterized by microcephaly, a distinct facial appearance, short stature, immunodeficiency, radiation sensitivity, and a strong predisposition to malignancy. Article contains family case of NBS that was complicated by lymphoma development with exitus lethalis in both children. Clear association between lymphoma and EBV-infection was examined in one child. Prenatal diagnostics of NBS was performed during four pregnancies in this family and three healthy children (heterozygous mutation carriers of 657del5 NBN'gene) were born.
Key words: Nijmegen syndrome, primary immunodeficiency, children, EBV'infection, lymphoma.
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