PERINATOLOGIYA I PEDIATRIYA.2014.2(58):16-20; doi 10.15574/PP.2014.58.16 
 

The frequency of intrauterine growth retardation and its impact on the course and prognosis of gastroschisis 

Slepov O. K., Grasyukova N. I., Veselsky V. L., Gordiyenko I. Yu., Soroka V. P., Ponomarenko O. P., Yermolova G. S., Palkina I. S., Markevych O. V.

SE «Institute of Pediatrics, Obstetrics and Gynecology», NAMS of Ukraine», Kiev, Ukraine

Nikolayevskaya regional children hospital, Nikolayev, Ukraine

The National Academy of Medical Sciences, Kiev, Ukraine 
 

Purpose — to investigate the physical development among the newborns with gastroschisis, to determine the growth retardation frequency of the intrauterine among them, its influence on viscero-abdominal disproportion development and treat forecasting this malformation. 
 

Patients and methods: it was analyzed the research results and the treatment among 30 newborns with gastroschisis in the surgical correction department of the congenital malformations among children SE «Institute of Pediatrics, Obstetrics and Gynecology» during 2006–2013 years. The general condition of these children rated with Apgar scale. The presence and the intrauterine degree of the retardation growth were defined according to Roberton N.K.R. tables, 1998. The accuracy influence of this delay on the viscero-abdominal disproportion development with gastroschisis and the surging correction forecast of this deformity were set with the angular transformation Fishers method. 
 

Results: among the newborns with gastroschisis it was diagnosed the intrauterine growth retardation in 56.7% cases. The asymmetric (hypotrophic) form of the intrauterine growth retardation was observed in 52.9% cases and the symmetric — in 47.1% cases. 
 

Conclusion: The intrauterine growth retardation has an influence on incidence of the viscero-abdominal disproportion with gastroschisis but hasn't an influence on its disproportions. The forecasting with gastroschisis hasn't depend on the presence or an absence of the intrauterine growth retardation. 
 

Key words: newborn babies, gastroschisis, intrauterine growth retardation, physical development. 
 

REFERENCES

1. Бисалиев БН. 2011. Оптимизация лечения гастрошизиса. Дис. … к мед н. Спец 14.01.19. М: 120.

2. Веселый СВ, Грона ВН, Перунский ВП и др. 2006. Методы диагностики и лечения гастрошизиса и омфалоцеле у детей (обзор литературы). Перинатология и педиатрия 3: 137—143.

3. Перунский ВП. 2008. Повышение эффективности хирургического лечения детей с гастрошизисом и омфалоцеле. Дис. … к мед н. Донецк: 149.

4. Плохих ДА. 2007. Хирургическое лечение гастрошизиса с висцероабдоминальной диспропорцией. Автореф. дис. … к мед н. Кемерово: 22.

5. Гойда НГ, Моісеєнко РО, Сулима ОГ та ін. 2002. Проблеми дитячої смертності в Україні. Охорона здоров'я України 2: 50—56.

6. Фофанов ОД. 2011. Лікування новонароджених та дітей раннього віку з вродженою обструктивною патологією травного тракту. Автореф. дис. … д мед н. Вінниця: 36.

7. Шабалов НП. 2006. Неонатология. М, Медпресс-информ І; гл. 3: 88—108.

8. Franchi-Teixeira AR, Weber Guimarаes BM, Nogueira B et al. 2001. Aminiotic fluid and intrauterine growth restriction in a gastroschisis fetal rat model. Fetal Diagn Ther 36: 366—367.

9. Bianchi A, Dickson AP, Alizai NK. 2002. Elective delayed midgut reduction — No anesthesia for gastroschisis: Selection and conversion criteria. J Pediatr Surg 37;9: 1334—1336.

10. Nicholas S, Tuuli MG, Dicke J et al. 2010. Estimation of fetal weight in fetuses with abdominal wall defects: comparison of 2 recent sonographic formulas to the Hadlock formula. J Ultrasound Med 29: 1069—1074.

11. Molik KA, Giangalewski CA, Grosfeld JL et al. 2001. Gastroschisis: a plea for risk categorization. J Pediatr Surg 36: 51—55.

12. Holland A, Walker K, Badawi N. 2004. Gastroschisis: an update. Pediatr Sur Int 26: 871—878.

13. Kazaura M, Lie R, Irgens L et al. 2004. Increasing risk of gastroschisis in Norway: an age-period-cohort analysis. Am J Epidemiol 159;4: 358—363.

14. Islam S. 2008. Clinical care out-comes in abdominal wall defects. Curr Opin Pediatr 20: 305—310.

15. Japaraj RP, Hockey R, Chan FY. 2003. Gastroschisis: can prenatal sonography predict neonatal outcome? Ultrtasound Obstet Gynecol 21: 329—333.

16. Loane M, Dolk H, Bradbury I. 2007. Increasing prevalence of gastroschisis in Europe 1980—2002: a phenomenon restricted to younger mothers? Pediatr Perinat Epidemiol 21: 363—369.

17. Srivastava V, Mandhana P, Pringle K et al. 2009. Rising incidence of gastroschisis and exomphalos in New Zealand. J Pediat Surg 44: 551—555.

18. Sekabira J, Hadley GP. 2009. Gastroschisis: a third world perspective. Pediatr Surg Int 25: 327—329.

19. Puligandla PS, Janvier A, Flageole H et al. 2001. The significance of intrauterine growth restriction is different from prematurity for the outcome of infants with gastroschisis. J Pediatr Surg. 36: 366—367.