HEALTH OF WOMAN. 2019.3(139): 49–52; doi 10.15574/HW.2019.139.49

Burka O. A., Tutchenko T. M., Shumytskyi A. V.
Bogomolets National Medical University, Kiev
SI «Institute of Pediatrics, Obstetrics and Gynecology named after academician O.M. Lukyanova NAMS of Ukraine», Kiev
MC DILA, Kiev

The article presents an analysis of data from the revision of the classification system of abnormal uterine bleeding (AUB) carried out by FIGO in 2019. According to this classification system, there are 9 groups of etiological factors of AUB, divided into 2 categories: mainly structural (polyp, adenomyosis, uterine myoma, malignant processes) and mainly functional (coagulopathy, ovulatory dysfunction, endometrial pathology, unclassified causes). This is characterized by the prevalence of certain causes in different age periods of the life of women, often a combination of several causes is present.

Contemporary possibilities of laboratory diagnostics of ovulatory dysfunctions, as well as endometrial pathologies, in particular chronic endometritis as often underestimated cause of AUB, are considered in detail.

Key words: AUB, ovulatory dysfunction, chronic endometritis, immunohistochemistry, CD138, sexually transmitted diseases.

REFERENCES

1. Munro MG, Critchley HOD, Fraser IS. (2011). The FIGO classification of causes of abnormal uterine bleeding in the reproductive years. Fertil Steril. 95(7):2204-2208.e3. https://www.sciencedirect.com/science/article/pii/S0015028211005097 https://doi.org/10.1016/j.fertnstert.2011.03.079

2. Munro MG, Critchley HOD, Fraser IS. 2018. FIGO Menstrual Disorders Committee. (2019). Corrigendum to «The two FIGO systems for normal and abnormal uterine bleeding symptoms and classification of causes of abnormal uterine bleeding in the reproductive years: 2018 revisions». Int J Gynecol Obstet 143:393-408. Int J Gynecol Obstet. 144(2):237–237. http://www.ncbi.nlm.nih.gov/pubmed/30609040 https://doi.org/10.1002/ijgo.12709

3. van den Brink MJ, Saaltink AL, Groenhof F, Kollen BJ, Berger MY, Lisman-van Leeuwen Y et al. 2017. Incidence and treatment of heavy menstrual bleeding in general practice. Fam Pract. 34(6):673–8. http://academic.oup.com/fampra/article/34/6/673/3861727 https://doi.org/10.1093/fampra/cmx050

4. Kolhe S. 2018. Management of abnormal uterine bleeding – focus on ambulatory hysteroscopy. Int J Womens Health 10:127–36. http://www.ncbi.nlm.nih.gov/pubmed/29606892 https://doi.org/10.2147/IJWH.S98579

5. Teede HJ, Misso ML, Costello MF, Dokras A, Laven J, Moran L et al. 2018. Recommendations from the international evidence-based guideline for the assessment and management of polycystic ovary syndrome. Hum Reprod. 33(9):1602–18. https://academic.oup.com/humrep/article/33/9/1602/5056069

6. Burka OA, Tutchenko TM. (2019). Modern approaches to diagnostics of hyperandrogenism distributed forms in reproductive aged women. Reprod Endocrinol. (46):39–45. http://reproduct-endo.com/article/view/168055

7. Amer M, El-Sokkary M, El-Shokry M, Mohamed H. (2013). The Prevalence of Chlamydia Infection in Patients with Chronic Endometritis. Ain Shams Med J. 64(10–12):767–78. http://platform.almanhal.com/CrossRef/Preview/?ID=2-68926 https://doi.org/10.12816/0013797

8. Toth M, Patton DL, Esquenazi B, Shevchuk M, Thaler H, Divon M. (2007). Association Between Chlamydia trachomatis and Abnormal Uterine Bleeding. Am J Reprod Immunol. 57(5):361–6. http://doi.wiley.com/10.1111/j.1600-0897.2007.00481.x https://doi.org/10.1111/j.1600-0897.2007.00481.x

9. Moreno I, Franasiak JM. (2017). Endometrial microbiota–new player in town. Fertil Steril. 108(1):32–9. https://www.sciencedirect.com/science/article/pii/S001502821730417X https://doi.org/10.1016/j.fertnstert.2017.05.034