Modern Pediatrics. Ukraine. (2021). 7(119): 63-71. doi 10.15574/SP.2021.119.63
Kramarov S. O., Yevtushenko V. V.
Bogomolets National Medical University, Kyiv, Ukraine

For citation: Kramarov SO, Yevtushenko VV. (2021). The role of azithromycin in the antibacterial therapy of acute respiratory infections in children. Modern Pediatrics. Ukraine. 7(119): 63-71. doi 10.15574/SP.2021.119.63.
Article received: Sep 06, 2021. Accepted for publication: Nov 09, 2021.

Acute respiratory infections are the leading cause of morbidity and mortality in childhood. Antibacterial therapy for acute respiratory infections should be prescribed carefully and under strict indications.
This review analyzes the etiological structure of diseases of the upper and lower respiratory tract, identifies modern views on the rational use of antibacterial agents in diseases such as acute tonsillopharyngitis, rhinosinusitis, bronchitis and pneumonia. Among the variety of antibacterial agents, macrolide drugs, in particular azithromycin, are most often used in pediatric practice. The pharmacological properties of azithromycin, mechanisms of its antimicrobial and immunomodulatory activity, indications for use in acute respiratory infections in children are considered in the article.
No conflict of interest was declared by the authors.
Key words: antibiotics, acute respiratory infection, macrolides, azithromycin, children.

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