Modern Pediatrics. Ukraine. (2022). 6(126): 110-118. doi 10.15574/SP.2022.126.110
Shevchuk Yu. V., Dieieva Yu. V., Dikhtiaruk O. V., Bondarenko Ya. V.
Bogomolets National Medical University, Kyiv, Ukraine

For citation: Shevchuk YuV, Dieieva YuV, Dikhtiaruk OV, Bondarenko YaV. (2022). Results of the analysis of epidemiological study of medical data on the effectiveness of Nasirus Sinus syrup in the complex therapy of acute viral and postviral rhinosinusitis in children. Modern Pediatrics. Ukraine. 6(126): 110-118. doi 10.15574/SP.2022.126.110.Article received: Jul 16, 2022. Accepted for publication: Oct 20, 2022.

In pediatric practice, the prevalence of rhinosinusitis (RS) depends on age: so, in the age category of 6-7 years old, acute RS at least 1 time per year old affects 8.5% of children, and at the age of 13-14 years old – 14.6%. Acute RS is one of the most common reasons for prescribing antibiotics, so correct treatment is extremely important, given the global crisis of antibiotic resistance. The tactics of treatment of acute RS depends on the form, nature of the inflammatory process and the presence of complications.
Purpose – to study the effectiveness of the plant-based dietary supplement Nasirus Sinus syrup in the complex therapy of children 3-11 years old with acute viral and postviral RS.
Materials and methods. Were analyzed medical data of 1176 children 3-11 years old who received outpatient therapy with a clinical diagnosis of “Acute viral RS” and “Acute postviral RS” (ICD-10: J01.9). The difference between these patients was only the duration of the disease.
Results. It has been established that the use of a plant-based dietary supplement Nasirus Sinus syrup in the complex therapy of children 3-11 years with acute RS helps to reduce subjective (nasal congestion, difficulty in nasal breathing, cough, snoring) and objective (mucous membrane hyperemia, postnasal drainage, rhinorrhea, wheezing, goopiness) manifestations of acute RS in a shorter time compared to the control group. The assessment of the severity of acute viral and postviral RS by Major Sinusitis Severity in absolute numbers in the main group was significantly different from the control group.
Conclusions. When using the complex therapy of acute viral and postviral RS in children 3-11 years with the inclusion of a plant-based dietary supplement Nasirus Sinus syrup, the results indicate a decrease in the manifestation of symptoms already on the 3^rd day of therapy, reliably demonstrates positive dynamics on the 5^th and 7^th days. Nasirus Sinus syrup should be recommended for use in children in the complex therapy of RS.
The research was carried out in accordance with the principles of the Helsinki Declaration. The study protocol was approved by the Local Ethics Committee of all participating institutions. The informed consent of the patient was obtained for conducting the studies.
No conflict of interests was declared by the authors.
Keywords: acute rhinosinusitis, children, herbal medicine, Nasirus Sinus syrup.

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