HEALTH OF WOMAN. 2016.4(110):84–90; doi 10.15574/HW.2016.110.84 
 

Regulatory and adaptative processes in the mother–placenta–fetus system in pregnants with neurovegetative disorders 
 

Vorobey L., Tkachuk R.

National Medical Academy of Postgraduate Education P. L. Shupyk, Kiev

Kiev city center of reproductive and perinatal medicine 
 

The objective: the impact of disadaptation changes of the mother–placenta–fetus system in pregnants with neurovegetative disorders on obstetric and perinatal complications frequency.

Patients and methods. 58 pregnant women with perinatal losses and neurovegetative disorders were examined during the trial. The clinical course of pregnancy and deliveries, newborns status, the hemodynamic and endocrine links changes of mother–placenta–fetus functional system were studied.

Results. The increased resistance and reduced hormone levels compared with control (p<0.05) were observed in pregnant women with neurovegetative disorders. Pregnancy and deliveries in women with neurovegetative disregulations are characterized by increased frequency of complications such as: placental dysfunction (1.3 times), fetal growth retardation (2.5 times), preterm deliveries (2.4 times), fetal distress (3 times), operative deliveries (2 times), postnatal newborns disadaptation.

Conclusion. A broked placentation, accompanied by functional failure of the mother–placenta–fetus system from early gestation with hemodynamic and endocrine disorders was established in pregnant women with neurovegetative disorders, which has an adverse effects on pregnancy, deliveries and fetus.

Key words: neurovegetative disorders, adaptive mechanisms, system mother-placenta-fetus, Doppler.

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