- Recurrent wheezing syndrome of preschool age (update 2017)
Recurrent wheezing syndrome of preschool age (update 2017)
SOVREMENNAYA PEDIATRIYA.2018.1(89):124-128; doi 10.15574/SP.2018.89.124
	Logvinova O. L.
	Kharkiv Medical University, Kharkiv, Ukraine
	The article is devoted to the topical issue of modern paediatric, which is wheezing. Overdiagnosis of asthma in children identified the purpose of the work, which is consisted in the analysis of the latest world literature sources on the unification of the diagnostic criteria and differential diagnosis of wheezing in chil1dren and the patients' management. A relatively new term for paediatrics in Ukraine, but widespread and introduced in the world clinical practice, is presented — «wheezing syndrome of preschool age» (in some sources — «recurrent wheezing syndrome»). The risk factors for the development of this syndrome, such as a significant number of allergens affecting a child during the first years of life and high sensitization of an individual to most of them, are defined in the work. The bronchial asthma risk index and the modified bronchial asthma risk index, which are partly dependent on the presence of «episodic virus-associated wheezing» or «recurrent wheezing caused by multiple triggers», have the practical significance with efficiency determination and usability. The preschool aged wheezing syndrome treatment efficacy is determined by the compliance between the physician, the child and their parents, including non-pharmacological and pharmacological therapy and ways of coping with treatment failure. Basic treatment of wheezing syndrome of preschool age includes inhaled glucocorticosteroids and leukotrienes (in children >2 years old), and the initial treatment of wheezing episodes complies with the principles of GINA12016.
	Key words: wheezing syndrome, recurrent wheezing, preschool children, bronchial obstruction, bronchial asthma.
	References
	1. Amin P., Levin L., Epstein T. et al. (2015). Optimum predictors of childhood asthma: persistent wheeze or the Asthma Predictive Index? J. Allergy Clin. Immunol. Pract. 2: 709—715. https://doi.org/10.1016/j.jaip.2014.08.009; PMid:25439361 PMCid:PMC4254628
2. Barros de Sousa R, Medeiros D., Sarinho E., Rizzo J. Â., Silva A.R. (2016). Risk factors for recurrent wheezing in infants: a case-control study. Rev. Saude Publica. 50: 15.
3. Beigelman A., Bacharier L.B. (2017). Management of preschool recurrent wheezing and asthma: a phenotype-based approach. Curr Opin Allergy Clin Immunol. 17(2): 131—138. https://doi.org/10.1097/ACI.0000000000000344; PMid:28118241 PMCid:PMC5560989
4. Belhassen M.J., De Blic L., Laurent L., Chanut-Vogel C. (2016). Recurrent Wheezing in Infants Medicine (Baltimore). 95 (15): 3404. https://doi.org/10.1097/MD.0000000000003404; PMid:27082618 PMCid:PMC4839862
5. Brand P.L., Baraldi E., Bisgaard H. et al. (2008). Definition, assessment and treatment of wheezing disorders in preschool children: an evidence-based approach. Eur Respir J. 32: 1096—1110. https://doi.org/10.1183/09031936.00002108; PMid:18827155
6. Brand P.L., Caudri D., Eber E. et al. (2014). Classification and pharmacological treatment of preschool wheezing: changes since 2008. Eur Respir J. 43: 1172—1777. https://doi.org/10.1183/09031936.00199913; PMid:24525447
7. Eber E., Midulla F. (2013). Рaediatric respiratory medicine. Hermes.
8. Global Strategy for Asthma Management and Prevention (2016 update). http://ginasthma.org/wp-content/uploads/2016/04/GINA-2016-main-report_tracked.pdf.
9. Lasso-Pirot A., Delgado-Villalta S., Spanier A.J. (2015). Early childhood wheezers: identifying asthma in later life. J. Asthma Allergy. 8: 63—73. PMid:26203265 PMCid:PMC4508083
10. Magnus M.C., Håberg S.E., Karlstad Ø. et al. (2015). Grandmother's smoking when pregnant with the mother and asthma in the grandchild: the Norwegian Mother and Child Cohort Study. Thorax. 70: 237—243. https://doi.org/10.1136/thoraxjnl-2014-206438; PMid:25572596 PMCid:PMC5034931
11. Martinez F.D. (2002). What have we learned from the Tucson Children's Respiratory Study? Paediatr Respir Rev. 3: 193—197. https://doi.org/10.1016/S1526-0542(02)00188-4
12. Tenero L.L., Tenero M., Piazza, Piacentini G. (2016). Recurrent wheezing in children. Pediatr. 5 (1): 31—36.
13. Zhang Q., Fu Z., Dai J., Geng G., Fu W., Tian D. (2017). Wheezing and Cough Caused by Double Aortic Arch, Not Asthm. Case Rep Cardiol. 4: 17.
 
       
  
  
  
  
  
 