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- HEALTH OF WOMAN WH_№4_2013
HEALTH OF WOMAN WH_№4_2013
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Nazarenko L.
Actual aspects for predicting, diagnosis, correction anomalies labor (review article).
12
The problem anomalies uterine contractions is relevant in the world always and everywhere, since the fre-quency of this pathology remains consistently high, are a major source of adverse obstetric and perinatal outcomes, fatal events. It is determining its practical and scientific significance. The paper presents new approaches and methods of diagnosis, prevention and regulation ineffective labor, presents actual ways to overcome obstetric aggression through personalized risk management.
Key words: delivery, contractivee activity, induction, preindcution.
Современные достижения и перспективы сохранения женского здоров’я.
19
Медичний форум у Львові.
20
Спиридонова Н. В.
Информационное письмо. О клинических преимуществах применения препарата Полижинакс в акушерстве и гинекологии.
21
Arbuzova S. B., Astahov V. M., Nikolenko M. I.
Strategy of prenatal screening for congenital and hereditary pathology within the framework of perinatal care.
23
Developments of prenatal diagnosis permit to detect a wide spectrum of congenital and hereditary pathology in early gestational age. It requires to set an optimal screening strategy, to provide standartization of every examinations’ stage, appropriate doctor’s training, system of quality control and audit. On the bases of 12-years own experience in prenatal diagnosis the main conditions for effective prevention of congenital birth defects were determined
Key words: prenatal diagnosis, prenatal genetic screening, congenital malformations, chromosomal pathology.
Kondratiuk V. K., Maidan I. S., Gorban N. E.
Magnesium deficiency and pregnancy (aspects of pathogenesis, clinical, pharmacological correction).
26
This paper presents an analysis of the basic pathogenesis, clinical course and rational, evidence-based pha-rmacological therapy wide range of physiological disorders in women as in step of pregravidary training, as during pregnancy, childbirth and lactation caused by a deficiency of magnesium in the body. From the stan-dpoint of evidence-based medicine proved an important role of this trace elements in the formation of a favo-rable psycho-somatic background of expectant mothers and prevention of serious perinatal complications.
Key words: magnesium, pregnancy, pregravidary training, hypomagnesaemia.
Палій І. Г.
Токсичний вплив антибіотиків на печінку. Правда чи міф?
30
Magas T. A., Loginova Ye. A., Vorobyova L. I.
Modern aspects of cervical cytology (review).
34
The social aspect of the dynamics of incidence of cervical cancer (CC) in Ukraine makes relevant the ques-tion its preventive. Cytological screening is an effective and affordable method of detection of cervical cancer and precancerous lesions. The evolution of ideas about the pathogenesis of cervical cancer and the role of human papilloma virus in this process become a prerequisite to the creation of The Bethesda System for evaluation of cervical samples. The questions of correspond to the individual units of terminology used in the various classifications, the expediency of using the new classification in Ukraine are considered.
Key words: cervix uteri, cytological screening, terminology, Bethesda system.
Benyuk V., Medvid V., Nykoniuk T., Koval S.
Specific of post-natal period conduct in cose of gestational varicose disease.
39
Application of Lioton -1000 of gel is an effective method of treatment chronic venous insufficiency in the post-natal period and promotes preventive maintenance trombofilicheskikh complications. Application of Lioton practically has no contra-indications in the postnatal period, unlike the majority tabletirovannykh forms veno-tonikov as does not render considerable system influence that allows to apply it in a lactation. Ease of appli-cation, reduction of such displays as a hypostasis, reddening, a pain, paresthesias, the itch, dryness of inte-guments do its almost irreplaceable at treatment of chronic venous insufficiency in the postnatal period.
Key words: chronic venous insufficiency, Lioton-1000 gel.
Романенко Т. Г., Чайка О. И.
Пренатальная диагностика в практике акушера-гинеколога.
44
Макаренко М. М., Говсеев Д. А., Аксенов В. Б.
Эффективная методика при кровотечениях во время кесарева сечения (РЕНИС II – ремоделирование нижнего сегмента матки).
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Статья посвящена проблематике кровотечений в акушерстве. Авторы описывают позитивные и нега-тивне стороны традиционных методик и раскрывают суть метода остановки кровотечений, который применяется на практике в родильном доме № 5 города Киева. Метод зарекомендовал себя, как высокоэффективный способ, позволяющий добиться значительных успехов в сохранении матки при гипотонии и предлежании плаценты.
Ключевые слова: кровотечения в акушерстве, 5-й роддом, потеря крови при кесаревом сечении.
Lebedyuk V. V., Zaharchenko L. G.
Experience with hepatoprotectors in preventing gestosiss.
50
A prophylactic treatment Hepatoprotectors Enerliv®. Established that the inclusion Enerliv® helps prevent preeclampsia, reduces the severity of its course and improve the effects of pregnancy and childbirth.
Key words: prevention, Enerliv®.
Islamova E.
Value of urine ph in clinical practice.
54
The analysis of urine ph value in clinical practice for the diagnosis of diseases of the urinary tract, as well as in the treatment of urogenital infections and kidney stones.
Key words: urine ph, urogenital infections, kidney stones.
Golyanovsky O. V., Kovalchuk E. V.
Modern aspects of the suppression of lactation post-abortion and post-partum periods.
56
Conducted studies to determine the effectiveness of a new dopamine receptor agonist hinagolid in order to suppress lactation in post-abortion and postpartum women with obstetric pathology. The high efficiency of the drug, few side effects, allowing it to be considered one of the drugs of choice for the suppression of lac-tation in obstetric pathology and congenital abnormalities of the fetus.
Key words: dopamine receptor agonist, hinagolid, post-abortion period, postpartum, lactation suppression.
Zaporozhan V. N., Tutrin I. I., Shpisman M. N., Dubinina V. G., Tarabrin O. A., Saleh E. N.
Dynamics of changes in hemostasis in combined thromboprophylaxis in pregnant women with severe preeclampsia.
59
Currently, pre-eclampsia in developing countries is a major cause of perinatal morbidity and mortality. Thro-mbotic complications that may develop on the background of severe preeclampsia, is a danger to life of the pregnant woman. Thus, the determination of the effective methods of thromboprophylaxis in severe preecla-mpsia is one of the most important issues of anesthesiology and intensive care.
Key words: thromboprophylaxis, hemostasis, pregnancy, severe preeclampsia.
Shpak I. V.
During labor in women infected with influenza virus.
64
306 women with an influenzal infection are surveyed. Distress a fetus is one of the basic displays of compli-cations at a virus infection. Weakness of patrimonial activity is diagnosed in 90,2% of cases, premature aut-flow amnion waters – in 77,5%, childbirth through natural patrimonial ways – in 53,9%, pathological bloodloos – in 27,3, abundance of water – in 54,9%, a syndrome of a growth inhibition of a fetus – in 58,8%. Pre-conseptional preparation, complex application of the standard and offered individual measures have lowered frequency premature removing a layer of placenta and sharp, chronic distress a fetus to 13,7%, weakness of patrimonial activity to 11,8%, premature autflow amnion waters – to 36,8%. Pathological bloodloos at the time of delivery through natural ways and at Cesarean section has made 9,7%. Signs abundance of water, a syndrome of a growth inhibition of a fetus have decreased in 2,3; 3,0 times accordingly.
Key words: childbirth, flu virus, pregnancy complication.
Zhigunova A. K.
Application of uroantiseptics in the treatment of diseases of the urinary system during pregnancy.
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The paper presents the current data on the prevalence, pathogenesis, effects of diseases of urinary system during pregnancy the basic principles of uro-antiseptics use in this period; the evidence base is given.
Key words: urinary system diseases, pregnancy, gestational pyelonephritis, preeclampsia.
Mamedalieva N. M., Raeva R. M.
Preventive measures and treatment of the varicose disease and its complications in obstetrics.
75
he aim of this research was to evaluate the effectiveness of Flebodia 600, the venotonic and angioprotector, in the treatment of pregnant women’s varicose disease and its complications. We observed thirty-six women with the varicose disease (Chronic Venous Insufficiency-0-I) in the 3rd trimester of pregnancy. All women passed duplex angioscanning with small vessels color Doppler mapping and Doppler metric examination of the uterine-fetus-placenta blood circulation. It was established that 70.6% of pregnant women with the vari-cose disease of the lower extremities had varicosity of the uterine veins. In 65,2% of observations we diag-nosticated the hemodynamical disorders in the system of the uterine-fetus-placental blood circulation of the pregnant women with the varicosity in the 3rd trimester. Against Flebodia 600, 80.5% of patients showed the regression of clinic symptoms of Chronic Venous Insufficiency, as well as 66.1% gave the normalization of indices for uterine-fetus-placenta hemodynamics. Thus, Flebodia 600, the venotonic and angioptrotector, provides many-sided effect to venous system of lower extremities and to the pregnant women’s, having vari-cose disease, hemodynamics state of uterine-fetus-placental blood flow, stimulating the reduction of disor-ders in the course of pregnancy and child-birth.
Key words: varicose disease, treatment, Flebodia 600.
Venskovskay I. B., Veropotvelyan Р. N., Veropotvelyan N. Р., Guzhevskaya I. V.
Pregnancy and chronical nephritis insufficiency.
77
In the overview article issues of the pathologenesis’ ethiology,classification of the clinical manifestations of chronical nephritis insufficiency(CNI) in pregnant are studied. The performed study of the publications shows the progress of CNI during a pregnancy and its negative impact on the advance of pregnancy as well as the state of health of the would-be mother,thus increasing the risk of the disease’ progress, addition of obstetrical and perinatal complications,the frequency of which is clearly connected with the stage of the chronical kidney disease (CKD), index of the arterial blood pressure and proteinurea. However,successes of neonathologists in leading the premature newborns let the obstetrical and neonatal prognosis be improved in particular pati-ents with CNI and give them the happiness of maternal blessedness.
Ключевые слова: беременность, хроническая почечная недостаточность.
Shlapak I. M.
Clinical-ehografical and morphological features of a «well-founded» and «insolvent» hem on uterus after cesarean section operation.
86
Results of the spent researches testify to presence essential clinical-ehografical and morphological features in the presence of «a well-founded» and «insolvent» hem on uterus after cesarean section operation. The received results are necessary for considering at method definition delivery women with hem on uterus after cesarean section.
Key words: hem on uterus, ehografia, morphology.
Puchkov V. A., Krut’ Y. Y.
Morphological changes of placenta for pregnant with the premature rup-ture of the amniotic membranes at preterm labor.
88
In this article the results of the morphological changes of placenta for pregnant with the premature rupture of the amniotic membranes at preterm labor. A risk in case of horioamnionitis factor is a presence of premature ruptured membranes , but not duration of waterless interval.
Key words: premature rupture of the amniotic membranes, chorioamnionitis, preterm labor.
Grishchenko O. V., Lakhno I. V.
The value of immunomodulating therapy in the treatment of patients with bacterial vaginosis.
90
It was performed the study of the efficacy of vaginal suppositories Hexiconum and immunomodulating drug Lavomax application in 56 patients with bacterial vaginosis. This method of therapy was effective in 95.5% of women surveyed by the 10 days of treatment thus provided the vaginal biotope resrtoration and prevented locus minori resistencia and recurrence.
Key words: bacterial vaginosis, treatment, Hexiconum, Lavomax.
Veropotvelyan P. N., Guzhevskaya I. V., Murashko K. V., Tsehmistrenko I. S., Veropotvelyan N. P.
Recurring cystitis in patients of the reproductive age.
95
On the basis of the made overview the article represents the results of the Ukrainian and foreign scientists, as well as own investigations on the role of the epidemiological significance of the cystitises conditioned by the growth of the chronic persistent forms which are stable to the traditional methods of influence. The op-pression of the cellular immunity may be conditioned by the following mechanism: active suppression, medi-ated by the activity (influence) of Th-2 antiphlogistic cytokines, deletion of immunocompetitive cells as a result of T-cells apoptose. A way of immunocorrective and ethiotrophic treatment of recurring cystitis is suggested.
Key words: recurrent cystitis, immunocorrective, causal treatment, bacteriuria, the effectiveness of treatment.
Prilutskaya A. B., Avramenko S. A., Prilutsky A. I., Prokopchuk O. P., Spiridonov K. V.
Clinical evaluation of the effectiveness of non-steroidal anti-inflammatory drug Dikloberl in the treatment of chronic pelvic inflammatory disease nonspecific etiology.
101
Based on the data of the study determined that the treatment of patients with chronic pelvic inflammatory disease (PID) Dikloberl helps limit manifestations of exudative inflammation, inactivation of mediators of inf-lammation, restoration of local immunity, which resulted in a statistically significant reduction in pelvic pain on a visual analog scale (VAS), and received 95.3% of the positive therapeutic effect, and allows us to recom-mend the drug for widespread use in gynecological hospitals.
Key words: chronic inflammatory disease of the pelvic organs, the treatment of non-steroidal anti-inflam-matory drugs, Dikloberl.
Kishakevich I. T.
Role of psychological and vegetative infringements in genezys a climac-teric syndrome.
104
Results of the spent researches testify that at women with displays of climacteric frustration the psychoso-matic infringements arising against raised uneasiness, increase neurotisme and emotional frustration take place. The role of psychological and vegetative factors in development of the climacteric syndrome which influence is reflected in a somatic condition of a female organism is besides defined, and leads to formation, first of all, psychosomatic infringements against dysfunction of vegetative nervous system. The received results allow to expand available data about patogenesise of climacteric infringements that it is necessary to consider by working out of algorithm of diagnostic and treatment-and-prophylactic actions.
Key words: psychological and vegetative infringements, a climacteric syndrome.
Pitko V. A., Loginova O. A., Tkachev A. I.
Effectiveness of new approaches in diagnostics and treatment of a weak ovarian response syndrome.
107
Until recently in diagnostics of a weak ovarian response syndrome both ultrasonic and hormonal methods of research were decisive, but that are not always allowed to answer the question: what will be the response of ovarian apparatus carried out on a controlled ovarian stimulation? Commonly diagnosed of a weak ovarian response syndrome is already installed in the process of the treatment on the fact of its development. Rati-onal approaches to the treatment of this pathological condition were absent. Doppler research of ovarian blo-od supply applied by us for diagnostic purposes has allowed to identify the contingent of patients at high risk for the development of a weak ovarian response syndrome, and proposed medical approaches developed in the form of a «modified» protocol achieved in 31,3% of pregnancies.
Key words: Doppler research, «modified» protocol, weak ovarian response syndrome.
Kolesnik A. V.
Clinical aspects of a combination ademyose and hyperplastic processes of endometrium at women of reproductive age.
109
Results of the spent researches testify that genetic predisposition, a condition relative or absolute hypere-strogenia, owing to hypofunction of ovariums, a metabolic syndrome, diseases of liver, chronic inflammatory diseases (genital and extragenital), promoting decrease in local and general immunity that leads to local infringement of maintenance of a constancy of cellular structure of fabrics of a uterus, change recettion an estrogen and a progesterone, are the most significant risk factors of development hyperplastic processes
of bodies of a reproduction. The received results are necessary for considering by working out of algorithm of diagnostic and treatment-and-prophylactic actions.
Key words: ademyose, hyperplastic processes of endometrium, clinic, reproductive age.
Poljuljah O. A.
Features of a painful syndrome and clinical semiology fibroze-cystes ill-nesses of mammary glands.
112
Results of the spent researches testify that at patients with fibrozecystes illness dependence of a painful syn-drome on age of patients, indicators of hormonal function of ovariums, developments parenhima and degre-es of its cyclic transformation takes place. The major factors influencing intensity mastalgia are a thickness parenhima and level of estradiole in blood whey in the second phase of menstrual cycle. The received re-sults are necessary for using by working out of algorithm of diagnostic and treatment-and-prophy-lactic acti-ons.
Key words: fibroze-cystes illness of mammary glands, a painful syndrome, clinical semiology.
Protsepko A. A., Adamchuk N. V.
Influence of hormonal rilizing-systems on Condition of mammary glands and cervix of uterus.
114
Results of the spent researches testify to high contraceptive efficiency hormonal rilizing systems, low level of various by-effects, and also about absence of negative influence hormonal rilizing systems on condition of mammary glands and cervix of uterus.
Key words: hormonal rilizing-systems, mammary glands, cervix of uterus.
Shamraj V. A.
Features of clinical-vegetative infringements at women with complex uterus pathology in postmenopausa.
117
Thus, at women postmenopausal age, having a metabolic syndrome, have authentically been more expres-sed complex complaints (from a number of the systems, transferred before anomaly of menstrual cycle) by comparison to similar indicators of patients without presence of a metabolic syndrome. Besides, it is possible to ascertain authentic prevalence of alarm in an actual mental condition, and also uneasiness as personal characteristic at women with displays of a metabolic syndrome. The share highalarm persons (a total point above 46) among women with complex pathology of a uterus and a metabolic syndrome was authentically above in comparison with women postmenopausal period without a metabolic syndrome. The received re-sults are necessary for considering by working out of algorithm of diagnostic and treatment-and-prophylactic actions.
Key words: clinical-vegetative infringements, complex uterus pathology, postmenopausal period.
Simrok V. V., Tananakina E. N.
Assessment of the dynamics the levels of estrogen and progesterone in women of reproductive age with abnormal uterine bleeding and concomi-tant extragenital pathology vita-melatonin while taking the drug.
120
The article presents the results of a prospective analysis of 96 cases of abnormal uterine bleeding in women of reproductive age, held stationary treatment in gynecological department of Feodosia maternity hospital. According to the results of the study suggests that use of the drug vita-melatonin during treatment of uterine bleeding facilitates synchronization of estrogen and progesterone in the dynamics, which is important for practical medicine.
Key words: uterine bleeding, reproductive age, extragenital pathology, estrogen, progesterone, melatonin.
Strahovetsky V. S.
Morfological features of pyoinflammatory diseases of appendages of a uterus.
125
Results of the spent researches testify, that the volume of operative intervention at pyoinflammatory diseas-es of appendages of a uterus depends on a pathogenetic variant of the given pathology, i.e. from presence intrauterine contraceptive and terms of its finding in a uterus cavity. The received results are necessary for considering by working out of tactics of operative treatment of pyoinflammatory diseases of appendages of a uterus.
Key words: pyoinflammatory diseases of appendages of uterus, morfology.
Tuchkina I. A., Tysyachka G. M.
A strategic approach to the complex treatment of inflammatory diseases genital organs in adolescent girls.
127
The results of examination and treatment of 126 adolescents with inflammatory processes of the female rep-roductive system between the ages of 11 and 18. The features of the clinical manifestations of genital inflam-mation, depending on age, presence of extragenital pathology identified in 84% of them, the microbial flora of the vagina, the hormonal profile of the body. Analyzed the use of combination therapy with an integrated drug Tazalok™ for the treatment of inflammatory processes of the female reproductive system in children and adolescents. High clinical efficacy of treatment with no side effects and complications.
Key words: adolescent girls, inflammation of the genital organs, treatment with Tazalok™.
Dynnik V. A.
Features of the maintenance of steroid hormones in patients with puber-tal uterine bleeding.
131
The results of studying 289 girls with pubertal uterine bleeding (PUB) have shown that the clinical course of the disease is associated with a set of sex steroids, namely: estradiol, estriol, and testosterone. Some fea-tures in the relations of steroid hormones have been determined in patients with different clinical variants of the disease. It has also been revealed that at the first episode of bleeding and during its remittent course E3 level significantly correlates with T, and close correlation between E2 and T is characteristic of the bleeding recurrences. The role of hormonal patterns in the mechanisms of development and clinical manifestation of the three different types of PUB has been discussed in the present article.
Key words: pubertal uterine bleeding, clinical course, sex steroid hormones.
Andriets O., Tsysar Y., Sydorchuk L.
Gene polymorphism GP IIIа in adolescent girls patients with juvenile uterine bleeding with thyroid pathologies.
135
The paper presents the peculiarities of juvenile uterine bleeding in women with concomitant thyroid disease and peculiarities of genetic predictors of this disease. Analyzed the frequency of genotypes gene glycopro-tein GP IIIa structure in pubertal menorahiy Women with concomitant thyroid pathologies.
Key words: uterine bleeding, teenage girls, thyroid gland, gene polymorphism of GP IIIa.
Feskov O., Chumakova N., Bezpechnaya I., Zozulina A., Ryzhkov A.
The value of mikrosalpinhoskopy in choosing therapeutic approach of women with tubal infertility.
139
Using of mikrosalpinhoskopy during laparoscopy allows to select the adequate tactics of management of patients with tubal-peritoneal form of infertility.
Key words: laparoscopy, mikrosalpinoskopy, infertility, IVF.
Vitiuk A. D., Hafiichuk R. G.
Individual approach to ovaries diagnosis in women with exhausted ovary syndrome.
141
The research work is devoted to increasing the efficiency of anovulatory infertility treatement by optimizing the algorithm of diagnostic, treatment and preventive measures for women with exhausted ovary syndrome in Assisted Reproductive Technology programs, using an improved program for ovulation stimulation. It has been established that, while the EOS progresses, blood concentrations of FSH, LH and estradiol increase, while the main ovarian reserve markers, i.e., anti-Mьllerian hormone and inhibin, as well as the size of both ovaries and the number of antral follicles decrease, which is the main cause for anovulatory infertility. The authors have proved the positive effect of an optimized algorithm of preparation to ovulation stimulation for women with anovulatory infertility and EOS on the active preparation and use of the suggested adjusted ART program, using a differential approach to medication correction, which has allowed a twofold increase in the efficiency of reproductive function treatment as compared to the conventional treatment methods and a reduction in the economic burden on the patients by 30,0%.
Key words: anovulatory infertility, exhausted ovary syndrome, ovarian reserve markers, medication correction.
Feskov A. M., Bezpechnaya I. M., Chumakova N. A., Somova E. V., Zhilkova Ye. S.
The effectiveness of treatment of patients wish thrombophilia in IVF programs.
147
We investigated the effect of thrombophilia on the pregnancy rate in assisted reproduction programs. We studied the peculiarities of patients with thromboрhiliа IVF and during pregnancy. Patients underwent correction of detected changes, leading to an increased incidence of pregnancy and childbirth, as well as to reduce the number of miscarriages and premature births.
Key words: thrombophilia, miscarriage, controlled ovulation induction, IVF.
Sudoma I. A., Kremenskaya Y. V., Pilip L. Y., Goncharova I. A., Zadorozhnaja T. D., Zukin V. D., Kilihevich S. N.
The autologous fat stem cells in the treatment of atrophic endometrium in women with infertility and the use of ART.
149
Patients with «thin endometrium» are a challenge group for the treatment of infertility using assisted repro-ductive technologies. In the paper the own experience of autologous fat stem cells application for the treat-ment of «thin endometrium» in patients with IVF failures are presented, morphological characteristics of the endometrium in these women are analyzed.
Key words: failed implantation endometrium is thin, fat stem cells.
Manzhura E. P., Vakulenko G. A., Mitskevich V. E., Harchenko E. V., Kornienko V. G., Klyusov A. N.
Current issues in the treatment of patients with cervical cancer.
157
The paper analyzes the complications arising from the combined and complex treatment of patients with cervical cancer stage 1. Describes the role and impact of radiation therapy on the development of these complications.
Key words: cervical cancer, complications of treatment.
Женское здоровье в жертву красоте.
160