• Prevention of obstetric and perinatal complications in pregnant women after in vitro fertilization on the background pathology of the thyroid gland
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Prevention of obstetric and perinatal complications in pregnant women after in vitro fertilization on the background pathology of the thyroid gland

HEALTH OF WOMAN. 2016.3(109):57–60 
 

Prevention of obstetric and perinatal complications in pregnant women after in vitro fertilization on the background pathology of the thyroid gland


Romanenko T. H., Chayka O. I.

National Medical Academy of Postgraduate Education P. L. Shupyk, Kiev


The objective: reduction in the incidence of obstetric and perinatal complications, dysfunctional states thyroid in pregnancy after IVF in the background of thyroid pathology.


Patients and methods. Studied during pregnancy, childbirth, postpartum, thyroid function, fetoplacental complex in women living in the Kiev region.


Results. The studies demonstrate the features of the thyroid gland, manifested in a slight decrease in the average level of free thyroxine fractions, triiodothyronine. Increased levels of placental lactogen, which provides high functional activity of the placenta in the second trimester indicates stress adaptation and compensatory mechanisms of the body. A direct correlation pituitary-tyreoidnoyi and placental systems.


Conclusion. In order to prevent iodine deficiency status of the mother, fetus and newborn, placental dysfunction and thyroid medication is recommended to correct complex Yodofol, which contains potassium iodide and folic acid of early pregnancy.


Key words: pregnancy, thyroid function, iodine deficiency, fetoplacental complex, placental dysfunction, prevention of hypothyroidism, Yodofol.


REFERENCES

1. World Health Organization/International Council for the Control of the Iodine Deficiency Disorders/United Nations Childrens Fund (WHO/ICCIDD/UNICEF). Assessment of the iodine deficiency disorders and monitoring their elimination. Geneva: World Health Organization, 2007.

2. Szybinski Z, Jarosz M, Hubalewska-Dydejczyk A et al. 2010, Jan-Feb. Iodine-deficiency prophylaxis and the restriction of salt consumption – a 21st century challenge. Endokrynol Pol. 61(1):135–40.

3. Zimmermann MB. 2009, Jun. Iodine deficiency. Endocr Rev. 30(4):376–408.

4. Triggiani V, Tafaro E, Giagulli VA et al. 2009, Sep. Role of iodine, selenium and other micronutrients in thyroid function and disorders. Endocr Metab Immune Disord Drug Targets 9(3):277–94.

5. Vdovichenko YuP, Kozodoy AV. 2009. Taktika vedeniya beremennosti u zhenschin s razlichnyimi formami gipotireoza i yododefitsita. Reproduktivnoe zdorove zhenschinyi 4:57–56.

6. Dreval AV, Shestakova TP, Nechaeva OA. 2009. Zabolevaniya schitovidnoy zhelezyi i beremennost. M, Meditsina.

7. Morugova TV, Stepanova EM. 2012. Osobennosti funktsionirovaniya schitovidnoy zhelezyi u beremennyih v usloviyah krupnogo promyishlennogo tsentra. Klinicheskaya tireodologiya 2;2:27–29.

8. Fadeev VV, Melnichenko GA. 2012. Diagnostika i lechenie gipotireoza vo vremya beremennosti. Akusherstvo i ginekologiya 4:41–43.

9. Shilin DE. 2010. Akusherskie aspektyi yodnogo defitsita i ego korrektsii. Consilium Medicum (pril. k zhurn.) 7:5–7.

10. Yan YQ, Chen ZP, Yang XM et al. 2009. Attention to the hiding iodine deficiency in pregnant and lactating women after universal salt iodization: A multi-community study in China. J Endocrinol Invest 28:547–53. http://dx.doi.org/10.1007/BF03347244

11. Zimmermann M, Aeberli I, Torresani T, Burgi H. 2010. Increasing the iodine concentration in the Swiss iodized salt program markedly improved iodine status in pregnant women and children: a 5-y prospective national study. Am J Clin Nutr 82(2):388–92.