PERINATOLOGIYA I PEDIATRIYA. 2017.1(69):26-32; doi 10.15574/PP.2017.69.26

Preterm birth: the impact on the health of women and children

Davydova Iu., Bondarenko N., Limanskaya A.

SI «Institute of Pediatrics, Obstetrics and Gynecology of NAMS of Ukraine», Kyiv

This article covers the modern approaches to the issue of preterm birth and their impact on the health of women and children. Based on the results of cohort and randomized studies conducted in recent years, it has been confirmed the immediate and delayed negative impact of preterm birth on the health not only of fetus, and of newborn, but also women's health in future, particularly on her cardiovascular system. Also common etiologic and pathogenetic mechanisms of preterm birth and formation of lesions in the cardiovascular system, including atherosclerosis, has been shown. The article presents data on the efficiency of modern pharmaceutical drugs (micronized progesterone) regarding the prevention of preterm birth in a high-risk group of pregnant women. The authors draw conclusions about the need of including the detailed cardiovascular examination and atherosclerosis prevention into the algorithm of preconception counseling and pregravid support for women with miscarriage previous history. The multidisciplinary team should be engaged (obstetrician, pediatrician, cardiologist) preconception counseling of such group of women.

Key words: preterm birth, heart diseases, micronized progesterone, preconception counseling.

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