• Onihomadezis as a manifestation of enterovirus infection
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Onihomadezis as a manifestation of enterovirus infection

SOVREMENNAYA PEDIATRIYA.2016.7(79):74-78; doi 10.15574/SP.2016.79.74 

Onihomadezis as a manifestation of enterovirus infection


Boyarchuk O. R., Volianska L. A., Dyvoniak O. M.

SHEI «I.Ya. Gorbachevsky Ternopil State Medical University», Ukraine

City Children's Hospital, Ternopil, Ukraine


Objective to study the clinical features of the infection episode in Ternopil for the period summer-autumn 2016.


Patients and methods. A total of 34 children with onihomadezis and average age (3.97±0.78) years underwent general clinical examination. In gender parity prevailed boys (55.88%).


Results. Manifestations of EI in children were corresponded to a typical (herpangina, epidemic myalgia, sudden rash and enteritis) and atypical (respiratory and conjunctivitis) forms. Anamnesticaly, in the 64.71% (n=22) of observed was marked short-term (1.87±0.92 days) increase in body temperature within37.6–40.0°C, although intoxication symptoms were found in all examined children. In 47.06% (n=16) of patients were recorded catarrhal symptoms, at most herpangina (32.35%, n=11), changes in the skin and mucous membranes differ by its morphology, size, color and rashes — at 44.12% (n=15), in 3 patients from all (8.82%) registered the appearance of macrolaminar peeling of feet and hands after 2–6 weeks. The same peeling recorded in 11 (32.35%) children without rashes in history. After 4–16 weeks after undergoing clinically diagnosed EI in children was marked asymptomatic lesions of hand and foot nail disorders. The number of infected nails at the time of examination was from 1 to 16. It is diagnosed various changes of hands and feet nails at different stages of development of pathological process: detachment of the nail plate in the growth area, deformation of the nail bed and also Meessa and Boa lines.


Conclusions. Enterovirus infection in children in the age 2–5 years has a mild course, as usual and does not leave serious consequences. Onihomadezis is a rare manifestation of EI, so children with such manifestations of infection need further follow-up.


Key words: enterovirus infection, children, onihomadezis.


REFERENCES

1. Antomonov MYu. 2006. Matematicheskaya obrabotka i analiz mediko-biologicheskih dannyih. Kiev: 558.

2. Kanaeva OI. 2014. Enterovirusnaya infektsiya: mnogoobrazie vozbuditeley i klinicheskih form. Infektsiya i immunitet. 4; 1: 27—36.

3. Lytvyn HO, Khomyn OIa. 2016. Osoblyvosti perebihu enterovirusnoi infektsii u ditei u Lvivskii oblasti vprodovzh 2015 roku. Science Rise: Medical Science. 5: 19—24.

4. Abedi GR, Watson JT, Pham H et al. 2015. Enterovirus and Human Parechovirus Surveillance – United States, 2009—2013. MMWR Morb Mortal Wkly Rep. 64; 34: 940—943.

5. De Crom SC, Rossen JW, van Furth AM, Obihara CC. 2016. Enterovirus and parechovirus infection inchildren: a brief overview. Eur J Pediatr. 175; 8: 1023—1029.

6. Bracho MA, Gonzalez-Candelas F, Valero A, Cordoba J. 2011. Enterovirus Co-infections and Onychomadesis after Hand, Foot, and Mouth Disease, Spain, 2008. Emerging Infectious Diseases. 17; 12: 2223—2231.

7. Shin JY, Cho BK, Park HJ. 2014. А Clinical Study of Nail ChangesOccurring Secondary to Hand-Foot-Mouth Disease: Onychomadesis andBeau's Lines. Ann Dermatol. 26; 2: 280—283.

8. Woolhouse ME, Howey R, Gaunt E et al. 2008. Temporal trends in the discovery of human viruses. Proс Вiol Sci. 275; 1647: 2111—2115.

9. Virus Taxonomy: 2013 Release. International Committee on