HEALTH OF WOMAN. 2020.5-6(151-152): 89-92; doi 10.15574/HW.2020.151-152.89
Zhabchenko I., Sudmak O., Bondarenko O., Kovalenko T., Lishchenko I.
SI «Institute of pediatrics, obstetrics and ginecology named academic Elena. M. Lukyanova NAMS of Ukraine»

In recent years, there is an increased number of reports on pregnancy and the first birth of women over 40 years and even 50 years in literature. Nowadays, the desire and opportunity to give birth to a child for the first time or again appeared in patients whose age has not leaved them a chance a decade ago. The tendency to increase the number of «late» pregnancies and births, which has become an objective reality of modern obstetrics, has significantly changed the attitude to this issue among doctors and in society as a whole. It is generally accepted that with increasing biological age, the number of diseases of the reproductive system increases that directly affects the possibility of pregnancy in a negative way.
Retrospective studies of pregnancy and childbirth in women of older reproductive age on the basis of SI «Institute of pediatrics, obstetrics and ginecology named after Academician OM Lukyanova National Academy of Medical Sciences of Ukraine» we found that 60% of pregnant women of late reproductive age had extragenital pathology that complicated the course of pregnancy and childbirth. The pathologies were mainly disorders of fat metabolism, especially in the group of women 40–46 years (51.8%) compared with the group of 35–39 (27.4%). Diseases of the gastrointestinal tract (28%), urinary system (22%) were also predominant in the group 40–46 years that together with disorders of fat metabolism and hyperlipidemia aggravated the course of pregnancy and increased the incidence of preeclampsia in older pregnant women.
The frequency of operative delivery in this group of women was consistently high and averaged at 68.4% that coincides with the data of world literature.
Following a decrease in the total number of births over the past 5 years and an increase in the number of pregnant women after 35 years with somatic pathology and high frequency of obstetric and perinatal complications, it is essential to optimize the antenatal care for this category of pregnant women.
Keywords: pregnancy, late reproductive age, obstetric complications, extragenital pathology, obesity, in vitro fertilization.

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