HEALTH OF WOMAN. 2015.8(104):130–134; doi 10.15574/HW.2015.104.130 

First -trimester Fetal Biometry of Mongolian Population 

Ochirpurev Bayanjargal, Pyrohova Vira Ivanivna, Gocho Mendsaikhan

Department of obstetrics and gynecology national Medical Institute, Mongolia

Lviv national medical University named Danylo Galitsky 

Background/Goals. This is the first study to construct the first trimester biometrical nomograms among Mongolian ethnic groups. 

Materials and Methods. In accordance with inclusion and exclusion criteria 1170 women between 5+5–13+6 weeks of gestation was scanned on crown-rump length (CRL) and 562 woman between 11–14+6 weeks of gestation examined on the following fetal biometric measurements: biparietal diameter (BPD), head circumference (HC), abdominal circumference (AC) and femur length (FL). Statistical analysis was performed with SPSS-21, E-View, and Windows Excel. A regression model was developed with CRL measurements and was compared to widespread nomograms in the world. 

Results. The obtained Mongolian first trimester standard fetal biometry compared to Hadlock from Europe, M.A.Esetov from the same geographic region, Osaka from Asia, ASUM from the reference of Australia. CRL was the same to other nomograms up to 9 weeks of gestational age. There is a 4–5 mm differences of Hadlock; 7 mm of Osaka at 10–12 weeks but the same with Campbell, 4 mm long of Campbell at 13 weeks.

BPD was 4–6 mm longer, HC was 20–13 mm longer than Hadlock but it was the same as others. FL was a bit shorter than Hadlock and ASUM but it was the same as Osaka and M.A.Esetov at 12–14+6 weeks of gestation. 

Conclusion. Difference with the obtained nomograms may be due to ethnic differences of the Mongolian fetal development. Current study shows that there are needs to use separate growth chart to estimate accurate gestational age for Mongolian population. 

Key words: Ultrasound, Gestational Age, Nomogram, Crown-Rump Length, Biparietal diameter, Head circumference, Abdominal circumference, Femur length. 

REFERENCES

1. Мэндсайхан Г. 2011. Нормальные показатели УЗИ плаценто-плодной системы у здоровых беременных-монголок. Автореф. дисс. д. мед. наук:14–39.

2. Chen Min. 2006. Application of ultrasonography in Early pregnancy.Thesis for the degree of Doctor of Philosophy at The University of Hong Kong:1–15.

3. Verburg B. 2007. Fetal Growth and Development. PhD, Erasmus University.

4. Graham Keith PARRY. Ethnic and Maternal Determinants of Fetal Growth in Normal Pregnancies. Thesis for the degree of MD at the University of Auckland 2011:1–50.

5. Vangen S, Stollenberg C, Skjaerven R, Magnus P, Harris JR, Stray-Pedersen B. 2002. Birthweight and perinatal mortality in different ethnic groups. Int J Epidemiol. 31.

6. Spencer K, Heath V, El-Sheikhah A, Ong CY, Nicolaides KH. 2005, May. Ethnicity and the need for correction of biochemical and ultrasound markers of chromosomal anomalies in the first trimester: a study of Oriental, Asian and Afro-Caribbean populations. Prenat Diagn. 25(5):365–9. PubMed PMID: 15906426.

7. Сhen M, Lam YH, Lee CP, Tang MH. 2004a. Ultrasound screening of fetal structuralabnormalities at 12 to 14 weeks in Hong Kong. Prenat Diagn 24(2):92–97.

8. Leary S, Fall C, Osmond C. 2006 (a). Geographical variation in relationships between parental body size and offspring phenotype at birth. «Acta Obstet Gynecol Scand 85».

9. Gary F. Cunningham. et al. Williams Obstetrics 21st Edition:745–757.

10. Эсетов МА. 2007. Ультразвуковая диагностика врождённых пороков развития плода в ранние сроки беременности:9–14.

11. Эсетов МА. 2002. Диагностика врожденных пороков развития плода в 10–14 недель беременности при скрининговом ультразвуковом исследовании: Тез. докладов VII съезда Российской ассоциации врачей ультразвуковой диагностики в перинатологии и гинекологии, 14–16 мая 2002 г., Астрахань. Пренатальная диагностика 1;3:239.

12. De Mucio B, Martinez G. 2011. CLAP/WR-PAHO/WHO. Monitoring fetal growth. 9-11.

13. Агентство при правительстве Монголии. Показатели уровня здоровья населения. 2013:3–13.

14. Жав Б, Лхагвасурэн Ж, Сарантуяа Ж, Үнэнцацрал Л. 2007. Акушерство:293–350.