SOVREMENNAYA PEDIATRIYA.2015.8(72):78-81; doi 10.15574/SP.2015.72.78 

Features of history and clinical-laboratory data in children with prolonged jaundice conjugation 

Tyazhka O. V., Zagorognya Y. M.

A.A. Bogomolets National Medical University, Kiev, Ukraine 

Objective — to study etiological factors, clinical course of prolonged jaundice and comorbidity of young children, to improve diagnosis, treatment and pre-

vention. 

Materials and methods. Under clinical observation were 37 children from 3 weeks to 2 months with prolonged jaundice conjugation. We studied the clinical and medical history of newborns and mothers, children's physical development and functional state of their organism. Complex investigetions were conducted, such as a complete blood count, blood biochemical (total bilirubin and fractions), urinalysis, coprogram, fecal bacteria overgrowth. Instrumental methods of examination are ultrasound examination of the abdomen, electrocardiogram, neurosonography. 

Results. The most powerful factors that contribute to the development and extension flow of jaundice in the neonatal period are threatened miscarriage and threat of premature birth in infants born by I of pregnancy and I of childbirth. The majority of births to mothers of children with prolonged jaundice, complications, for example cesarean section, uterine inertia, rapid delivery, premature rupture of membranes. The most common comorbidities in children with prolonged jaundice are a hypoxic-ischemic lesion of the central nervous system syndrome, hypotension, cephalohematoma, intestinal dysbiosis, and mild anemia. 

Conclusion. Given the nature of pregnancy and childbirth, in each case, it is possible to prevent the development of prolonged jaundice in the baby. Timely conduct the necessary examination of the child to prevent the development of jaundice and prescribe a treatment. 

Key words: prolonged neonatal jaundice, comorbidities, young children. 

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