HEALTH OF WOMAN. 2019.2(138): 67–69; doi 10.15574/HW.2019.138.67

Polyulyakh O. A.
Shupyk National Medical Academy of Postgraduate Education, Kiev

The objective: to study features of a course of pregnancy, labors and a functional condition of fetoplacental complex at women with the combined pathology of uterus and mammary glands.

Materials and methods. It was carried out complex clinical-laboratory and functional inspection 120 women who depending on existence of benign pathology of mammary glands and were parted on corresponding at groups and subgroups. In complex of the conducted researches were included clinical, ekhografical, dopplerometrical, cardiotocografical, endocrinological, biochemical and statistical.

Results. Results of research testify to existence of direct dependence of frequency of obstetric and perinatal complications respectively from existence of the combined pathology with the obvious prevails at combination of diffuse dysplasia of mammary glands and an adenomyosis. Results of complex assessment functional condition of fetoplacental complex at patients with the combined pathology testify to existence of features of placental dysfunction which is absent at patients only with diffuse dysplasia of mammary glands, gains the compensated character at combination to uterus leiomyoma, and at a combination to an adenomyosis are the main reason of high frequency of perinatal pathology owing to placental dysfunction.

Conclusion. The received results needs to be considered when developing algorithm of diagnostic and treatment-and-prophylactic actions at women with the combined pathology of uterus and mammary glands.

Key words: pregnancy, labors, fetoplacental complex, diffuse dysplasia of mammary glands, uterus leiomyoma, adenomyosis.

REFERENCES

1. Zaporozhan VM, Hladchuk IZ, Rozhkovska NM ta in. 2014. Novi tekhnolohii u khirurhichnomu likuvanni hlybokoho infiltratyvnoho i poverkhnevoho perytonealnoho endometriozu. Reproduktyvnaia еndokrynologiia 2 (16): 7–9.

2. Zakharenko NF, Kovalenko NV, Manoliak IP. 2015. Do pytannia kompleksnoi terapii endometriozu. Reproduktyvna endokrynolohiia 3 (23): 28–33.

3. Vandermeulen L, Cornelis A, Kjaergaard Rasmussen C et al. 2017. Guiding histological assessment of uterine lesions using 3D in vitro ultrasonography and stereotaxis. Facts Views Vis Obgyn. 9 (2): 77–84.

4. Ferenczy A. 2018. Pathophysiology of uterine patology. Hum Reprod Update.  4: 312–322. https://doi.org/10.1093/humupd/4.4.312; PMid:9825847

5. Benson RC, Sneeden VD. 2017. Dysplasia of mammary glands and adenomyosis: a reappraisal of symptomatology. Am J. Obstet Gynecol. 76: 1044–1057. https://doi.org/10.1016/0002-9378(58)90186-8

6. Klinicheskie rekomendatsii. Akusherstvo i ginekologiya. Pod red. Savelevoy GM, Serova VN, Suhih GT. 4-e izd., pererab. i dop. M, GEOTAR-Media: 1024. 2015.

7. Zaporozhan VM, Chaika VK, Markin LB ta in. 2013. Akusherstvo ta hinekolohiia: u 4-kh t.: natsionalnyi pidruchnyk za red. akad. NAMN Ukrainy, prof. V.M. Zaporozhana. K, VSV «Medytsyna»:1032 + 4 s. kolor. vkl.

8. Nakaz MOZ Ukrainy vid 02.11.2015 r. № 709 «Pro zatverdzhennia ta vprovadzhennia medyko-tekhnolohichnykh dokumentiv zi standartyzatsii medychnoi dopomohy pry vysokomu perynatalnomu ryzyku (Unifikovanyi klinichnyi protokol pervynnoi, vtorynnoi (spetsializovanoi) medychnoi dopomohy «Vysokyi perynatalnyi ryzyk».