Paediatric surgery.Ukraine.2021.1(70):90-93; doi 10.15574/PS.2021.70.90
Khanes G. S.^1,2, Kuzmin L. V.¹, Denisenko L. I.², Tarasenko A. P.², Pehnio T. V.², Zhuk S. I^3
1National Children’s Specialized Hospital «OKHMATDYT», Kyiv, Ukraine
²Kyiv City Maternity Hospital No 2, Ukraine
³Shupyk National Medical Academy of Postgraduate Education, Kyiv, Ukraine

For citation: Khanes GS, Kuzmin LV, Denisenko LI, Tarasenko AP et al. (2021). Experience in the treatment of early neonatal parasitic sepsis in the maternity hospital. Paediatric Surgery.Ukraine. 1(70):90-93; doi 10.15574/PS.2021.70.90.
Article received: Aug 31, 2020. Accepted for publication: Feb 14, 2021.

Early neonatal sepsis mainly has bacterial etiology – 84%, less often fungal – 12%, otherwise – viral and parasitic etiology. According to the European Center for Disease Control and Prevention (CDC), the occurrence of sepsis in newborns is closely related to birth weight and gestational age, as well as skin color. It was established, in particular, that the most severe types of sepsis occur in children weighing 400–1500 g at birth and less than 30 weeks of gestation. Parasitic sepsis in newborns refers to severe forms of childhood sepsis, with mortality reaching high. The article presents the experience of successful treatment of 2 newborns in a maternity hospital both were non-transportable. At the beginning of treatment, the anamnesis of pregnancy was thoroughly studied. From the first day of the disease, both patients underwent a comprehensive instrumental (ultrasound, X-ray) and laboratory (PCR, ELISA, procalcitonin, coagulogram, CRP and general biochemistry tests) examinations. One child – prematurely born at 30 weeks of gestation with a weight of 1070 grams – was treated for intrauterine chlamydial sepsis. The second suffered from intrauterine toxoplasmotic sepsis and Rhconflict; the latter was treated in utero at 30 weeks of gestation. Both patients were treated by a multidisciplinary team and the children recovered.
Conclusions. The results of treatment show effectiveness pathogen approach to the treatment of severe sepsis in newborns.
The research was carried out in accordance with the principles of the Declaration of Helsinki. The permission of the parents of the children was obtained
to conduct the research.
The authors declare no conflicts of interest.
Key words: newborn, intrauterine, parasitic sepsis, chlamydia, toxoplasmosis.

REFERENCES

1. Angus Derek. (2012). Sepsis in the developing world: lessons for a small planet. Speaker abstracts. Paris. Sepsis: 11.

2. ChavezBueno S, Mc Culloh RJ. (2018). Current Trends in Epidimiology and Antimicrobial Resistans in Epimiology and Antimicrobial Resistance in Neonatal Sepsis. JeanLouis Vincent Editor. Annual Update in Intensive Care and Emergency Medicine: 39–52. https://doi.org/10.1007/978-3-319-73670-9_4

3. Khanes GS, Maksakova IS, Liutko OB. Mitiakina IYu, Horelik VV. (2019). Diagnostic and treatment of bone and joint sepsis in newborns. Collection of Science works. Innovations technology in Pediatric surgery and Intensive Care. Kyiv: 66–67.

4. Khanes GS. (2012). Questions of pathofisiology and diagnostic of pediatric sepsis. Sbornic publication. 8th annual. Moskovskaya conference «Gnoino-septicheskie zabolevania u detey» Russian and SNG countri’s: 60–63.

5. Koltsova IG, Trubina LM, Tishechkina VO, Zubkova IN, Mischenko VP, Davidovich FD. (2003). Role of toxaplosmosis in occurrence of a pathology in pregnant and fetus. Pediatric, Obstetric and Gynecology. 3: 79–83.

6. Moore SW, Wright C. (2011). The Role of antenatal placental infections in Necrotizing Enterocolitis (NEC) – A Pilot study. Abstract of 9th PAPSA Сeip-Town. Biennale Conference: 17.

7. Randolf AG. (2018, Oct 1). Sepsis in Children. Sepsis 2018. Speaker abstract: 24.

8. Zaplatnikov AL, Korovina NA, Korneva MYu, Chebukin AV. (2013). Russian Medical Academy of Postgraduate Education. Intrauterin infection: diagnosis, treatment, prevention. Emergency Medicine. 1 (48): 25–33.