Ukrainian Journal of Perinatology and Pediatrics. 2023. 1(93): 6-11; doi 10.15574/PP.2023.93.6
Romanenko T. G., Shaganov P. F.
Shupyk National Healthcare University of Ukraine, Kyiv

For citation: Romanenko TG, Shaganov PF. (2023). Effectiveness of treatment of tubal-peritoneal infertility in women of reproductive age. Ukrainian Journal of Perinatology and Pediatrics. 1(93): 6-11; doi 10.15574/PP.2023.93.6.
Article received: Dec 07, 2022. Accepted for publication: Mar 13, 2023.

Purpose – to evaluate the effectiveness of the treatment of patients with infertility and tubo-peritoneal ruptures based on the analysis of long-term treatment results (occurrence of uterine pregnancy).
Materials and methods. 132 women with tubo-peritoneal infertility were examined, who were divided into 2 groups: the Group 1 included 68 patients before and after operative laparoscopy, who received our proposed algorithm; the Group 2 included 64 patients before and after operative laparoscopy, who received generally accepted medical and preventive measures. The condition of the operated women was monitored for 1 year: 62 patients of the Group 1 and 57 patients of the Group 2. The frequency of pregnancy after treatment for 6 months and 6-12 months was evaluated.
Results. Out of 62 women in the Group 1, 28 (45.2%) patients became pregnant within 6 months versus 11 (19.2%) in the Group 2 (p<0.05), and from 6 to 12 months – 13 (20.9%) patients versus 8 (14.1%) in the Group 2 (p<0.05). In 2 (3.5%) patients of the Group 2, the pregnancy was ectopic, which can be considered as a negative consequence of the treatment of adhesions and tubal-peritoneal infertility in general. If pregnancy did not occur in the examined women within a year, they were offered assisted reproductive technologies as the most effective method of pregnancy.
Conclusions. The proposed pathogenetic prevention of recurrence of adhesive process in the pelvis of women of reproductive age is effective, can be reasonably used and allows to increase the frequency of pregnancy in the first 6 months of the postoperative period by 2.4 times in case of stage I-II prevalence of adhesive process.
The research was carried out in accordance with the principles of the Helsinki Declaration. The study protocol was approved by the Local Ethics Committee of the institution mentioned in the paper. The informed consent of the patient was obtained for conducting the studies.

No conflict of interests was declared by the authors.
Keywords: tubo-peritoneal infertility, peritoneal pelvic adhesions, prevention of sebaceous process, pregnancy.

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