PERINATOLOGIYA I PEDIATRIYA.2013.4(56):103–104

Correlative interactions of organochlorine pesticides content in the different biosubstrates of mother and fetus in conditions of background pollution in crimean region

Moskovchuk O. B., Moskovchuk K. M., Evstafyeva E. V.

State Institution «S.I. Georgievskyi Crimea State Medical University», Simferopol, Ukraine

Central Regional Clinical Hospital of Simferopol region, Ukraine

Objective: definition and correlation analysis of concentration distribution in the different biosubstrates.

Patients and methods. A total of 35 «mother — newborn» pairs without deviations in delivery were examined. The content of organochlorine pesticide dichlorodiphenyltrichloroethane and its metabolites, hexachlorocyclohexane and its isomers, hexachlorobenzene in 5 biosubstrates (maternal venous blood, umbilical cord blood, hair, placenta and mother's breast milk) are determined by gas chromatography.

Results. It is shown not only a high detection of organochlorine pesticides in all biosubstrates but statistically significant correlation interactions between their concentrations in different and also in the similarly-named biosubstrates.

Conclusions. Maximum number of correlations were found between biosubstrates «venous blood — breast milk», «venous blood — mothers hair», «blue blood — the blood of the umbilical cord. «For several pairs of comparison was shown the absence of significant correlations of organochlorine pesticides.

Key words: organochlorine pesticides, biosubstrates.

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