HEALTH OF WOMAN. 2016.2(108):127–130; doi 10.15574/HW.2016.108.127 
 

Correlational relationship of psychological and hormonal status in women with chronic pelvic pain 
 

Nochvina O. A.

Vinnitsa national medical University M. I. Pirogov 
 

The purpose of the study: the study of correlations between the level of basic gonadotropic and steroid hormones in follicular phase of the menstrual cycle and concentration of serotonin in women with chronic pelvic pain syndrome.

Materials and methods. A study of the major markers of chronic stress and hormonal status by the immunoassay method in women with chronic pelvic pain of the main group and healthy women of the control group with further study of the correlation between the obtained indicators.

Results. It has been established that women with chronic pelvic pain have a statistically significant increase of serotonin, epinephrine and norepinephrine, which indicates a constant activation of the stress response system and reflects the disintegration of the adaptive processes. The hormonal profile of women with chronic pelvic pain is characterized by dysfunction of the hypothalamic-pituitary-ovarian system, namely the imbalance in the secretion of basic tropic pituitary hormones in different phases of menstrual cycle – FSH, LH, reduced concentrations of estradiol and progesterone and a moderate increase of prolactin and cortisol. In the study of correlational relationship the influence of neurotransmitters on the major steroid and sex hormones has been proved.

Conclusion. In the study of the formation of pathogenetic links of chronic pelvic pain syndrome is necessary to study the correlation between the level of serotonin, a basic steroid and sex hormones in women with this pathological condition for establishing relations of psychological and hormonal status.

Key words: chronic pelvic pain syndrome, psychological status, hormonal profiles, correlational relationship.

REFERENCES

1. Belova AN, Krupin VN, ed. 2007. Chronic pelvic pain: guidance for doctors. Moscow:571.

2. Wayne AM. 1997. Clinical aspects of emotional stress. Emotional stress: Theoretical and Clinical aspects. edited by Sudakov KV, Petrov VI. Volgograd: 138-148, 154-157.

3. Vyhlyaeva EM. 1998. Guide to endocrine gynecology. Moscow, MYA: 258.

4. Gadyeva FG. 2001. Relationship of immune and endocrine systems in women of reproductive age. Obstetrics and gynecology 1:11-13.

5. Hremlyng C, Auerbah C. 2002. Workshop on management of stress. SPb., Peter:240.

6. Zhuk SI, Dzis NP. 2007. Noninflammatory disease of organs – new views on the known problem. Women’s health 4(32):122-126.

7. Zaitsev VN, Lyflyandsky VG, Marynkyn VI. 2006. Applied Medical Statistics. St. Petersburg:432.

8. Kaminsky VV, Zhuk SI, Sinenko NA et al. 2008. To the question of ensuring the monitoring of the hormonal status of women. Reproductive women’s health 2(36):49-52.

9. Kettayl VM, Arch GA. 2001. Pathophysiology of the endocrine system. SPb. Moscow: Nevsky Dialect BINOM:336.