- Congenital diaphragmatic hernias in children older than 1 month of life: features of clinical course and diagnostics, treatment tactics
Congenital diaphragmatic hernias in children older than 1 month of life: features of clinical course and diagnostics, treatment tactics
Paediatric Surgery (Ukraine). 2026. 1(90): 67-75. doi: 10.15574/PS.2026.1(90).6775
Sliepov Ie. O., Danilov O. A.
Center for Neonatal Surgery of Developmental Malformations and Their Rehabilitation of SI "All-Ukrainian Center for Motherhood and Childhood of the NAMS of Ukraine", Kyiv
For citation: Sliepov IeO, Danilov OA. (2026). Congenital diaphragmatic hernias in children older than 1 month of life: features of clinical course and diagnostics, treatment tactics. Paediatric Surgery (Ukraine). 1(90): 67-75. doi: 10.15574/PS.2026.1(90).6775.
Article received: Nov 06, 2025. Accepted for publication: Mar 16, 2026.
Aim – to analyze the clinical features and diagnostic outcomes of congenital diaphragmatic hernias (CDH) detected after the neonatal period and to develop a diagnostic algorithm for them.
Materials and methods. A retrospective review of medical records was conducted for 27 children aged 1.5 months to 13 years with late-diagnosed CDH who were treated at the Department of Pediatric Surgery.The study analyzed the patients’ age and sex, the type and location of the hernia, clinical manifestations, associated congenital anomalies, and the results of diagnostic and therapeutic procedures. For diagnosis, X-ray, ultrasound, and endoscopic methods were used, as well as computed tomography and magnetic resonance imaging when indicated. Statistical analysis of the results was performed using descriptive statistics.
Results. Late-diagnosed CDH were identified in 27 (15.9%) of 170 children with CDH, specifically Bochdalek’s hernia in 21 (77.8%) patients and Morgagni’s hernia in 6 (22.2%). Clinical manifestations were varied and nonspecific, with respiratory and gastrointestinal symptoms — or a combination thereof — predominating. The primary diagnostic method was plain radiography of the chest and abdomen in two projections. When X-rays were insufficiently informative, contrast-enhanced X-ray studies, ultrasound, computed tomography, or magnetic resonance imaging were used. Based on the results obtained, a diagnostic algorithm for late-detected CDH was developed.
Conclusions. Late-diagnosed CDH are characterized by a polymorphic clinical picture, which often leads to a delay in diagnosis. The primary diagnostic method is a chest and abdominal X-ray in two projections, while additional imaging methods are used as indicated to confirm the diagnosis and plan surgical intervention. The proposed diagnostic algorithm makes it possible to optimize the evaluation of children with suspected CDH, shorten the time to diagnosis, and timely determine the indications for surgical treatment.
The study was conducted in accordance with the principles of the Declaration of Helsinki. Informed consent was obtained from the parents or legal guardians of the children participating in the study.
The authors declare no conflict of interest.
Keywords: children, congenital diaphragmatic hernia, Bochdalek hernia, Morgagni hernia, diagnosis, diagnostic algorithm, treatment strategy.
REFERENCES
1. Ackerman KG, Vargas SO, Wilson JA et al. (2012). Congenital diaphragmatic defects: proposal for a new classification based on observations in 234 patients. Pediatric and Developmental Pathology. 15: 265-274. https://doi.org/10.2350/11-05-1041-OA.1; PMid:22257294 PMCid:PMC3761363
2. Algadi G, Saxena AK. (2019). Laparoscopic Morgagni hernia repair in children: systematic review. Journal of Pediatric Endoscopic Surgery. 1: 85-90. https://doi.org/10.1007/s42804-019-00029-6
3. Altinkaya N, Parlakgumus A, Koc Z, Ulusan S. (2010). Morgagni hernia: diagnosis with multidetector computed tomography and treatment. Hernia. 14(3): 277-281. https://doi.org/10.1007/s10029-009-0608-9; PMid:20033748
4. Anadolulu Aİ, Gerçel G, Kocaman OH. (2020, May 30). Laparoscopic repair of Morgagni hernia in children. Ann Med Surg (Lond). 56: 7-10. https://doi.org/10.1016/j.amsu.2020.05.012; PMid:32551107 PMCid:PMC7292882
5. Arslan S, Okur MH, Azizoglu M et al. (2024). Late presentation of Bochdalek hernia in children experience at a single centre. South African J. of Surgery. 62: 261-266. https://doi.org/10.36303/SAJS.00159
6. Bawaziz OA, Mahomed A, Fayyad A et al. (2020). Laparoscopic-assised repair of Morgagni hernia in children. Ann. Pediatr Surg. 16: 1-7. https://doi.org/10.1186/s43159-020-00022-2
7. Beznea P, Campeanu A, Strimbu T. (2021). Diagnostic challenges in late presenting diaphragmatic hernia. Romanian J. of Military Medicine. CXXIV(4): 533-540. https://doi.org/10.55453/rjmm.2021.124.4.17
8. Deshpande VP, Totla RJ, Pawar AA, Suryawanshi PR. (2021). Spontaneous rupture of sac in Bochdalek hernia leading to acute intestinal obstruction. Afr J Paediatr Surg. 18: 104-105. https://doi.org/10.4103/ajps.AJPS_79_20; PMid:33642409 PMCid:PMC8232363
9. Dingeldein M. (2018, Aug). Congenital diaphragmatic hernia: management & outcomes. Adv Pediatr. 65(1): 241-247. https://doi.org/10.1016/j.yapd.2018.05.001; PMid:30053927
10. Ergun E, Gollu G, Ates U et al. (2020). Laparoscopic assisted anterior transabdominal wall closure using loop suture removing technique in Morgagni hernia: safe and easy method. Pediatr. Surg. Int. 36(6): 679-685. https://doi.org/10.1007/s00383-020-04658-4; PMid:32342179
11. Escarcega P, Riquelme MA, Lopez S et al. (2018). Multi-institution case series of Pediatric Patients with laparoscopic Repair of Morgagni Hernia. Journal of laparoendoscopic Advanced Surgical Techniques. 28(8): 1019-1022. Epub 2018 Apr 5. https://doi.org/10.1089/lap.2017.0621; PMid:29620946
12. Esposito C, Escolino M, Varlet F et al. (2017). Technical standartization of laparoscopic repair of Morgagni diaphragmatic hernia in children: results of a multicentric survey on 43 patients. Surg. Endosc. 31: 3320-3325. https://doi.org/10.1007/s00464-016-5365-0; PMid:27924390
13. Garriboli M, Bishay M, Kiely EM et al. (2013). Recurrence rate of Morgagni diaphragmatic hernia following laparoscopic repair. Pediatr Surg Int. 29(2): 185-189. https://doi.org/10.1007/s00383-012-3199-y; PMid:23143132
14. Ghabisha S, Ahmed F, Al-Wageeh S et al. (2021). Delayed presentation of congenital diaphragmatic hernia: a case report. Pan African Med. J. 40(1): 2-4. https://doi.org/10.11604/pamj.2021.40.242.32113; PMid:35233262 PMCid:PMC8831220
15. Golden J, Baery WE, Jang G et al. (2017). Pediatric Morgagni diaphragmatic hernia: a descriptive study. Pediatr. Surg. Int. 33(7): 771-775. Epub 2017 Mar 13. https://doi.org/10.1007/s00383-017-4078-3; PMid:28289880
16. Hamid R, Baba AA, Shera AH et al. (2014, Apr-Jun). Late-presenting congenital diaphragmatic hernia. 11(2): 119-123. https://doi.org/10.4103/0189-6725.132799; PMid:24841010
17. Ibi K, Ogata S, Kondo K, Namai Y. (2022, Jan). Late-presenting congenital diaphragmatic hernia associated with poor weight gain. Pediatr Int. 64(1): e14730. Epub 2021 Oct 12. https://doi.org/10.1111/ped.14730; PMid:34637581
18. Kajal P, Bhutani N, Goyal M, Kamboj P. (2017). Iatrogenic gastric perforation in a misdiagnosed case of late presenting congenital diaphragmatic hernia. Report of an avoidable complication. International Journal of Surgery Case Reports. 41: 154-157. https://doi.org/10.1016/j.ijscr.2017.09.027; PMid:29078158 PMCid:PMC5742013
19. Karadag CA, Erginel B, Yildiz A et al. (2023). Laparoscopic repair of Morgagni hernia in children. J. Pediatr Surg. 58(9): 1670-1673. https://doi.org/10.1016/j.jpedsurg.2023.01.045; PMid:36804105
20. Kim DJ, Chung JH. (2013, Sep). Late-presenting congenital diaphragmatic hernia in children: the experience of single institution in Korea. Yonsei Med J. 54(5): 1143-1148. https://doi.org/10.3349/ymj.2013.54.5.1143; PMid:23918563 PMCid:PMC3743178
21. Kitano Y, Lally KP, Lally PA, Congenital diaphragmatic hernia study group. (2005). Late-presenting congenital diaphragmatic hernia. J Pediatr Surg. 40: 1839-1843. https://doi.org/10.1016/j.jpedsurg.2005.08.023; PMid:16338301
22. Kosinski P, Wielgos M. (2017). Congenital diaphragmatic hernia: pathogenesis, prenatal diagnosis and management – literature review. Ginekologia Polska. 88(1): 24-30. https://doi.org/10.5603/GP.a2017.0005; PMid:28157247
23. Lim L, Gilyard SM, Sydorak RM et al. (2019). Minimally Invasive Repair of Pediatric Morgagni Hernias Using Transfascial Sutures with Extracorporeal Knot Tying. Perm. J. 23: 18.208. https://doi.org/10.7812/TPP/18.208; PMid:31926567 PMCid:PMC6836568
24. Loria G, Peri FM, Fabrizio DD et al. (2022). Robotic approach to Morgagni-Larrey hernia in pediatric surgery: a case report. APMP. 110(1). doi: 10.13129/1828-6550/APMB/110.1.2022.
25. Mbaye P.A., Gneye D., Fall M. et al. Prise en charge de la hernie diaphragmatique congénitale en Afrique sub Saharienne: l'expérience du Centre Hospitalier National d'Enfants Albert Royer au Sénégal. Pan African Medical Journal. 2022; 41:185. https://doi.org/10.11604/pamj.2022.41.185.30907; PMid:35655674 PMCid:PMC9120748
26. Muien MZA, Jeyaprahasam K, Krisnan T, Ng CY, Teh YG. (2021, Jul 6). Rare late-presentation congenital diaphragmatic hernia mimicking a tension pneumothorax. Radiol Case Rep. 16(9): 2542-2545. https://doi.org/10.1016/j.radcr.2021.06.024; PMid:34276850 PMCid:PMC8264534
27. Obata S, Souzaki R, Fukuta A et al. (2020). Which is the better Approach for Late – Presenting Congenital Diaphragmatic Hernia: Laparoscopic or Thoracoacopic? A single Institution Experience of more than 10 Years. J. of Laparoendoscopic & Advanced Surgical Techniques. 30(9): 1-7. https://doi.org/10.1089/lap.2019.0162; PMid:32716256
28. Okur MH, Aydoglu B, Azizoglu M et al. (2022). A novel scarless laparoscopic method for Morgagni hernia repair. Nigerian Journal of Clinical Practice. 25(9): 1517-1522. doi: 10.4103/njcp.njcp_36_22. https://doi.org/10.4103/njcp.njcp_36_22; PMid:36149213
29. Ortiz RJ, Manso MA, Reusmann A et al. (2025). Laparoscopic repair of Morgagni hernia in children. Tips and tricks learned in 20 years experience at a tertiary pediatric center. Cir Pediatr. 38: 38-44. https://doi.org/10.54847/cp.2025.02.11; PMid:40196877
30. Shin HB, Jeong Y-J. (2020). Diagnostic Considerations of Late Presenting Co0ngenital Diaphragmatic Hernia in children: Single Center Experience. Adv. Pediatr. Surg. 26(1): 11-14. https://doi.org/10.13029/aps.2020.26.1.11
31. Slepov O, Kurinnyi S, Ponomarenko O, Migur M. (2016). Congenital retrosternal hernias of Morgagni: Manifestation and treatment in children. African Journal of Pediatric Surgery. 13/2: 57-62. https://doi.org/10.4103/0189-6725.182557; PMid:27251653 PMCid:PMC4955447
32. Soomro S, Mahtam I, Abbasi BM, Dodani M. (2022). Strangulated left Bochdalek diaphragmatic hernia: a lesson learned. J Ayub Med Coll Abbottabad. 34; 4 Suppl 1: 1030-1032. https://doi.org/10.55519/JAMC-04-S4-9804; PMid:36550668
33. Rattan KN, Singh J, Dala P. (2019). Diagnostic challenges in late presenting congenital diaphragmatic hernia a 16 year experience from tertiary care centre in North India. Tropical Doctor. 49(2):138-141. Epub 2019 Feb 10. https://doi.org/10.1177/0049475519827109; PMid:30739552
34. Tartar T, Saraç M, Bakal Ü, Kazez A. (2018). Bochdalek hernias in children with late presentation. Turk Pediatri Ars. 53(4): 245-249. https://doi.org/10.5152/TurkPediatriArs.2018.0039; PMid:30872927 PMCid:PMC6408192
35. Torfs CP, Curry CJ, Bateson TF, Honore LH. (1992, Dec). A population – based study of congenital diaphragmatic hernia. Teratology. 46(6): 555-65. https://doi.org/10.1002/tera.1420460605; PMid:1290156
36. Veenma DCM, De Klein A, Tibboel D. (2012). Developmental and genetic aspects of congenital diaphragmatic hernia. Pediatr. Pulmonol. 47: 534-545. https://doi.org/10.1002/ppul.22553; PMid:22467525
37. Vinton V, Pasa M, Kelly MN et al. (2024, May 15). Beyon of the Neonate: a delayed presentation of congenital diaphragmatic hernia in a 17-year 0 old. Hindawj Case Reports in Pediatrics. 2024: 7518183. https://doi.org/10.1155/2024/7518183; PMid:38779305 PMCid:PMC11111302
38. Wang C, Lin X, Shu Z et al. (2023). Single-site laparoscopic ligation of the hernia sac in infants with congenital Morgagni hernia. Front Pediatr. 11: 1078244. https://doi.org/10.3389/fped.2023.1078244; PMid:36896400 PMCid:PMC9989263
39. Yuan M, Li F, Xu C et al. (2019). Thoracoscopic treatment of late-presenting congenital diaphragmatic hernia in infants and children. J Laparoendoscopic & Advanced Surgical Techniques. 29(1): 77-81. https://doi.org/10.1089/lap.2018.0025; PMid:30300095
