1

MEDICAL PUBLICATION
CONFERENCES AND SEMINARS
MARKETING RESEARCH

  • Comparison of structural organization medulla oblongata of human fetus from the towers of the skull with human fetuses without anomalies for improvement prenatal diagnosis of congenital malformations central nervous system
en To content

Comparison of structural organization medulla oblongata of human fetus from the towers of the skull with human fetuses without anomalies for improvement prenatal diagnosis of congenital malformations central nervous system

PERINATOLOGIYA I PEDIATRIYA. 2016.3(67):85-88; doi 10.15574/PP.2016.67.85 
 

Comparison of structural organization medulla oblongata of human fetus from the towers of the skull with human fetuses without anomalies for improvement prenatal diagnosis of congenital malformations central nervous system


Tikholaz V. O.

N.I. Pirogogov Vinnitsia National Medical University, Ukraine


Purpose — to determine morphometric parameters structures medulla fetal human skull tower with gestational age 20–21 weeks of fetal development and compare the findings with those in fetuses without malformations.


Patients and methods. An anatomical and histological study of the medulla oblongata in 17 human fetuses aged 20–21 weeks of fetal development and fetal human skull from the tower. Preparations medulla after fixing poured into blocks and stained with hematoxylin-eosin, toluidine blue and the Van-Gison. Using computer histometry morphometric parameters determined structures of the medulla oblongata.


Results. Establish the sensory, motor and autonomic nuclei of the medulla oblongata, and the form and degree of differentiation of neurons in the fetal skull tower and fetuses without anomalies. Comparison of morphological parameters and structure of the medulla oblongata human fetus 20–21 weeks of fetal development of the skull tower and fetuses without anomalies.


Conclusions. In the fetus oxycephalus established differences in size and shape of the nuclei of the medulla oblongata (lower olive nucleus complex, dorsal nucleus of the vagus) and the size and degree of differentiation of neurons in the nucleus hypoglossal nerve and the solitary tract nucleus.


Key words: oxycephalus, morphometric parameters, nucleus of the medulla oblongata, prenatal ontogenesis.


REFERENCES

1. Kirilova LG. 2004. Prenatal diagnosis of congenital malformations and hypoxic-ischemic lesions of the central nervous system of the fetus at this stage. Ukrayinskiy medichniy chasopis. 5(43): 98–102.

2. ShkolnIkov VS, GumInskiy YuY, Tikholaz VO. 2014. Comparison of morphological characteristics of spinal cord segments from human fetal spina hernia and human fetuses without malformations. 18;1(69): 138–144.

3. Kimonis V, Gold JA, Hoffman TL, Panchal J, Boyadjiev SA. 2007, Sep. Genetics of craniosynostosis. Semin Pediatr Neurol. 14(3): 150–161. http://dx.doi.org/10.1016/j.spen.2007.08.008; PMid:17980312

4. Kabbani H, Raghuveer TS. 2004, June. Craniosynostosis. Am Fam Physician. 69(12): 2863-2870. PMid:15222651

5. Bannink N, Nout E, Wolvius EB, Hoeve HL, Joosten KF, Mathijssen IM. 2010, Feb. Obstructive sleep apnea in children with syndromic craniosynostosis: long-term respiratory outcome of midface advancement. Int J Oral Maxillofac Surg. 39(2): 115–121. http://dx.doi.org/10.1016/j.ijom.2009.11.021; PMid:20056390