PERINATOLOGIYA I PEDIATRIYA.2015.2(62):29-31;doi10.15574/PP.2015.62.29

Clinico-immunological characteristics of the course congenital viral infections in newborns

Redko I. I.

Zaporozhye Medical Academy of Postgraduate Education, Zaporozhye, Ukraine

Purpose. To study the clinic-immunological characteristics of the course congenital viral infections in newborns.

Patients and methods. Generally examined 834 woman and their sick newborns suspiciously on congenital viral infections. The main group consisted of 224 newborns with congenital viral infections, control group — 30 healthy newborns. On the base of etiological verification determine virological options and main clinical forms of congenital viral infections, the condition of humoral and cellular immunity, interferon status in acute period of infections is studied.

Results. Found, that at congenital viral infections predominate mixt-forms. In acute deseases we have established an reduction CD3+, CD4+, CD19+, suppression factor, functional activity neutrophils, deficit of interferon status at clinical forms of congenital viral infections in newborns.

Conclusion. Change the performance of humoral and cellular immunity, interferon status depend from clinical and etiological forms of intentions. The severe affection of immunity systems to detect of mixt-viral-TORCH-infections.

Key words: congenital viral infections, newborns, immunity.