• Acute appendicitis in newborns (literature review and own data)
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Acute appendicitis in newborns (literature review and own data)

Ukrainian Journal of Perinatology and Pediatrics. 2023. 1(93): 108-112; doi 10.15574/PP.2023.93.108
Konoplitskyi V. S., Slipchuk K. I., Korobko Yu. Ye.
National Pirogov Memorial Medical University, Vinnytsia, Ukraine

For citation: Konoplitskyi VS, Slipchuk KI, Korobko YuYe. (2023). Acute appendicitis in newborns (literature review and own data). Ukrainian Journal of Perinatology and Pediatrics. 1(93): 108-112; doi 10.15574/PP.2023.93.108.
Article received: Nov 30, 2022. Accepted for publication: Mar 13, 2023.

Most often, acute appendicitis occurs in premature babies. The mortality rate from neonatal acute appendicitis in 2000 was 25-28%. Most often, the cause of inflammation of the appendix in newborns is a local form of necrotizing enterocolitis.
Purpose – is to provide up-to-date information and to familiarise a wide range of medical professionals with the current issues of diagnosis and treatment of acute appendicitis in newborns.
Acute appendicitis in newborns has a similar course to necrotizing enterocolitis. However, it should be noted that treatment tactics for these diseases are different. Necrotic enterocolitis in the absence of perforation and peritonitis is treated with conservative methods, while appendicitis is treated surgically in all cases.
Ultrasound diagnosis has an advantage over computed tomography because it does not have a radiation burden on the newborn, so it is recommended as the first line of diagnosis among other imaging methods.
In the case of appendage perforation, an important method is inspection radiography and the search for free gas in the abdominal cavity (52% of appendage perforations are visualized by inspection roentgenography). Сonclusions. Due to the rare occurrence of acute appendicitis among newborns, doctors may be less wary of this pathology, which often causes significant changes in the child's body and is a frequent cause of septic conditions due to the rapid spread of the inflammatory process due to the anatomical and physiological characteristics of newborns. The speed of diagnosis and medical care, the correct determination of treatment tactics directly reduces the frequency and severity of postoperative complications, including purulent inflammatory diseases of the abdominal cavity and abdominal wall, as well as adhesive disease and adhesive intestinal obstruction in the first place.
No conflict of interests was declared by the authors.
Keywords: appendicitis, peritonitis, necrotizing enterocolitis of newborns, newborns, neonatal surgery.
REFERENCES

1. Arroyo IC, de Alarcón García JR, Ramos JP, Ramírez LÁ, Amillo ED, Beauregard CS. (2021). Neonatal appendicitis: how many sides does this coin have? Cir Pediatr. 34 (3): 143-146.

2. Belyayev MK, Fedorov KK, Belyayev AM. (2022). Ostryyappenditsit u novorozhdennykh-oslozhneniyeili MORBUS SUI GENERIS? Scientist. S4 (22): 7-8.

3. Bocharov RV, Pogorelko VG, Yushmanova AB, Karavayev AV, Semchenko EA. (2020). Klinicheskiye sluchai ostrogo appenditsita u novorozhdennykh. Rossiyskiy vestnik detskoy khirurgii. Anesteziologii I reanimatologii. 10 (2): 203-208. https://doi.org/10.17816/psaic600

4. Botman T, Ruys PJ. (1963). Amoebic Appendicitis in a Newborn Infant. Tropical and Geographical Medicine. 15 (2): 221-224.

5. Dias J, Cerqueira A, Pinheiro L, Rezende D, Sá C, Abreu E et al. (2013). Acute neonatal appendicitis: the potential value of laparoscopy as a diagnostic and therapeutic tool. Case Reportsin Perinatal Medicine. 2 (1-2): 83-85. https://doi.org/10.1515/crpm-2012-0072

6. Hill WB, Mason CC. (1925). Prenatal appendicitis with rupture and death. American Journal of Diseases of Children. 29 (1): 86-87. https://doi.org/10.1001/archpedi.1925.04120250089009

7. Jahangiri M, Hosseinpour M, Jazayeri H, Mohammadzadeh M, Motaharizad D, Mirzadeh AS. (2013). Perforated acute appendicitis in a pre-term neonate. Iranian Red Crescent Medical Journal. 15 (6): 497. https://doi.org/10.5812/ircmj.4629; PMid:24349748 PMCid:PMC3840837

8. Konoplitskyi VS, Pogorilyi VV, Dymchina UA, Michalchyk TI, Korobko UYe. (2020). Analysis of reasons for dissemination of destructive forms of acute apendicitis in children. Paediatric Surgery.Ukraine. 2 (67): 43-47. https://doi.org/10.15574/PS.2020.67.43

9. Koynov YuYu, Gramzin AV, Krivosheyenko NV, Pavlushin PM, Tsyganok VN, Chikinev YuV. (2020). Klinicheskiye variant abdominalnoy khirurgicheskoy patologii u nedonoshennykhdetey. Detskaya khirurgiya. 24 (6): 403-408. https://doi.org/10.18821/1560-9510-2020-24-6-403-408

10. Mehrpisheh S, Farhadi R, Kiasari ME, Hesam F. (2022). Neonatal appendicitis in northern Iran: A case report. Clinical Case Reports. 10 (8): e6232. https://doi.org/10.1002/ccr3.6232

11. Meigher SC, Lucas AW. (1952). Appendicitis in the newborn: case report. Annals of Surgery. 136 (6): 1044. https://doi.org/10.1097/00000658-195212000-00021; PMid:12986693 PMCid:PMC1802363

12. Nabiyev BB, Khudoyberdiyev DK. (2020). Anatomiya plodnykh organov limfoidnoy systemy cheloveka (obzor literatury). Dostizheniya nauki i obrazovaniya. 16 (70): 15-24.

13. Olkhova EB, Kartseva EV, Kuznetsova EV, Kirsanov AS, Dzemeshko EV. (2015). Ostryy appenditsit u novorozhdennogo (klinicheskoye nablyudeniye). Radiologiya-praktika. 3: 54-59.

14. Raveenthiran V. (2015). Neonatal appendicitis (part 1): a review of 52 cases with abdominal manifestation. Journal of neonatal surgery. 4: 1. https://doi.org/10.47338/jns.v4.157

15. Raveenthiran V. (2015). Neonatal appendicitis (part 2): A review of 24 cases with inguinoscrotal manifestation. Journal of Neonatal Surgery. 4: 2. https://doi.org/10.47338/jns.v4.168

16. Razumovskiy AYu, Dronov AF, Smirnov AN, Golovanev MA. (2013). Ostryy appenditsit u detey. Rossiyskiy vestnik detskoy khirurgii, anesteziologii I reanimatologii. 3 (4): 125-132.

17. Sachwitz D, Hass HJ, Aumann V, Herrmann K, Krause H. (2009). Incidental finding of an acute appendicitis in a premature newborn with haematochezia. Zentral blatt fur Chirurgie. 134 (6): 557-559. https://doi.org/10.1055/s-0028-1098922; PMid:20020390

18. Sarzosa A, Rodríguez J, Quizhpe E, Espinosa C, Teran E. (2019). Appendicitis in a baby born to a woman with preeclampsia. Journal of Pediatric Surgery Case Reports. 51: 101320. https://doi.org/10.1016/j.epsc.2019.101320

19. Tumen A, Chotai PN, Williams JM, Myers-Webb A, Krishnan R, Eubanks III JW. (2017). Neonatal perforated appendicitis attributed to localized necrotizing enterocolitis of the appendix: a review. Journal of Neonatal Surgery. 6: 3. https://doi.org/10.21699/jns.v6i3.535; PMid:28920020 PMCid:PMC5593479