HEALTH OF WOMAN. 2015.8(104):42–44 

Vaginal hormone releasing system – a modern solution to urgent problems 

Vovk I. B., Kondratyuk V. K., Gorban N. E.

SI «Institute of Pediatrics, Obstetrics and Gynecology, NAMS of Ukraine», Kiev 

The paper presents the review of literature and my own observations of the modern approach to prevent unwanted pregnancies and healthfulness effect of the vaginal hormonic releasing system NuvaRing on the female body. The thorough examination of the effectiveness, safety, nosotropic mechanism of the given contraceptive components action and the additional non-contraceptive effects is expounded. 

Key words: family planning, contraception, efficiency, safety, releasing system NovaRing®. 

REFERENCES

1. Державна програма «Репродуктивне здоров’я нації на 2006–2025 роки» (проект). Здоровье женщины 2:9–6. 2006.

2. Планування сім’ї: навч. посіб. За ред. НЯ Жилки, ІБ Вовк. 3-е вид., доп. К. 2010:300.

3. Адамова ГМ, Бондаренко ОА, Гойда НГ та ін. 2012. Сучасні аспекти планування сім’ї. Посібник. К:320.

4. Венцківський БМ, Вовк ІБ, Воробйова ЛІ та ін. 2007. Пероральні гормональні контрацептиви: клінічне керівництво. К:36.

5. Післяпологове та післяабортне планування сім’ї: навч. посіб. За ред. НЯ Жилки. К. 2007:193.

6. Надання жінкам послуг, пов’язаних з абортом: клініко-організаційне керівництво. За ред. НЯ Жилки. К. 2006:108.

7. Подольский ВВ, Вовк ИБ, Корнацкая АГ. 2010. Актуальные проблемы репродуктивного здоровья женщин в Украине. Здоровье женщины 4(50):121–126.

8. Wieder DR, Pattimakiel L. 2010, Nov 12. Examining the efficacy, safety, and patient acceptability of the combined contraceptive vaginal ring (NuvaRing). Int. J. Womens Health 2:401–409. http://dx.doi.org/10.2147/IJWH.S6162; PMid:21151688 PMCid:PMC2990910

9. Hatcher RA, Trussell J, Nelson AL, Cates W, Stewart F. 2007. Contraceptive Technology – New York: Ardent Media.

10. Merki-Feld GS, Hund M. 2007. Clinical experience with NuvaRing in daily practice in Switzerland: cycle control and acceptability among women of all reproductive ages. Eur. J. Contracept. Reprod. Health Care 12:240–247. http://dx.doi.org/10.1080/13625180701440180; PMid:17763262

11. Madden T, Blumenthal P. 2007. Contraceptive vaginal ring. Clin. Obstet. Gynecol. 50(4):878–85. http://dx.doi.org/10.1097/GRF.0b013e318159c07e; PMid:17982330

12. Kerns J, Darney P. 2011. Vaginal ring contraception. Contraception. 83(2):107–115. http://dx.doi.org/10.1016/j.contraception.2010.07.008; PMid:21237335

13. Brucker C, Karck U, Merkle E. 2008. Cycle control, tolerability, efficacy and acceptability of the vaginal contraceptive ring, NuvaRing: results of clinical experience in Germany. Eur. J. Contracept. Reprod. Health Care 13:31–38. http://dx.doi.org/10.1080/13625180701577122; PMid:17853162

14. Novбk A, de la Loge C, Abetz L, van der Meulen EA. 2003. The combined contraceptive vaginal ring, NuvaRing: an international study of user acceptability. Contraception. 67(3):187–194. http://dx.doi.org/10.1016/S0010-7824(02)00514-0

15. Paresi RJ, Myers RS, Matarasso A. 2015. Contraceptive Vaginal Rings: Do They Pose an Increased Risk of Venous Thromboembolism in Aesthetic Surgery? Aesthet. Surg. J. 35(6):721–727. http://dx.doi.org/10.1093/asj/sju166

16. Brache V, Faundes A. 2010. Contraceptive vaginal rings: a review. Contraception. 82(5):418–27. http://dx.doi.org/10.1016/j.contraception.2010.04.012; PMid:20933115

17. Caruso S, Cianci S, Malandrino C. 2014. Quality of sexual life of women using the contraceptive vaginal ring in extended cycles: preliminary report. Eur. J. Contracept. Reprod. Health Care. 19(4):307–314. http://dx.doi.org/10.3109/13625187.2014.914488; PMid:24856308

18. Caruso S, Malandrino C, Cicero C. 2013. Quality of sexual life of women on oral contraceptive continued-regimen: pilot study. J. Sex. Med. 10(2):460–466. http://dx.doi.org/10.1111/j.1743-6109.2012.03004.x

19. Nguyen BT, Jensen JT. 2014. Evaluating the efficacy and safety of a progestin- and estrogen-releasing ethylene vinyl acetate copolymer contraceptive vaginal ring. Expert. Opin. Drug. Saf. 13(10):1423–1430. http://dx.doi.org/10.1517/14740338.2014.948842; PMid:25106828

20. Sulak PJ, Smith V, Coffee A, Witt I. 2008. Frequency and management of breakthrough bleeding with continuous use of the transvaginal contraceptive ring. Obstet. Gynecol. 112:563–571. http://dx.doi.org/10.1097/AOG.0b013e3181842071; PMid:18757653

21. Roumen FJ. 2008. Review of the combined contraceptive vaginal ring, NuvaRing. Ther. Clin. Risk. Manag. 4(2):441–451.

22. Bitzer J. 2012. The vaginal ring (NuvaRing®) for contraception in adolescent women. Gynecol. Endocrinol. 28(2):125–129. http://dx.doi.org/10.3109/09513590.2011.579665; PMid:21615237

23. Nappi C, Bifulco G, Tommaselli GA, Gargano V, Di Carlo C. 2012. Hormonal contraception and bone metabolism: a systematic review. Contraception. 86(6):606–621. http://dx.doi.org/10.1016/j.contraception.2012.04.009; PMid:22717184

24. Abu Hashim H, Alsherbini W, Bazeed M. 2012. Contraceptive vaginal ring treatment of heavy menstrual bleeding: a randomized controlled trial with norethisterone. Contraception. 85(3):246–252. http://dx.doi.org/10.1016/j.contraception.2011.07.012; PMid:22067765

25. Liu KE, Alhajri M, Greenblatt E. 2011, Sep. A randomized controlled trial of NuvaRing versus combined oral contraceptive pills for pretreatment in in vitro fertilization cycles. Fertil Steril. 96(3):605–8. http://dx.doi.org/10.1016/j.fertnstert.2011.06.073; PMid:21880278

26. Friend DR. 2011, Jun. Intravaginal rings: controlled release systems for contraception and prevention of transmission of sexually transmitted infections. Drug Deliv Transl Res. 1(3):185–93. http://dx.doi.org/10.1007/s13346-011-0024-4; PMid:25788239

27. Edwardson J, Jamshidi R. 2010. The contraceptive vaginal ring. Semin. Reprod. Med. 28(2):133–139. http://dx.doi.org/10.1055/s-0030-1248138; PMid:20352563

28. Dinger J, Mцhner S, Heine-mann K. 2013. Cardiovascular risk associated with the use of an etonogestrel-containing vaginal ring. Obstet. Gynecol. 122(4):800–808. http://dx.doi.org/10.1097/AOG.0b013e3182a5ec6b; PMid:24084537