- A case of successful treatment of severe catheter-related gram-negative sepsis in the young child
 
A case of successful treatment of severe catheter-related gram-negative sepsis in the young child
SOVREMENNAYA PEDIATRIYA.2016.7(79):20-25; doi 10.15574/SP.2016.79.20
A case of successful treatment of severe catheter-related gram-negative sepsis in the young child
Semkovych M., Semkovych Ya., Synoverska O.
State higher educational institution «The Ivano-Frankivsk National Medical University», Ukraine
	
	The child having serious catheter-related gram-negative sepsis has been treated in the Department of anesthesiology and intensive therapy (DAIT) of the regional children's clinical hospital (RCCH) of Ivano-Frankivsk. From the anamnesis, it is known that infusion therapy through peripheral venous catheter in the projection of the left crook of the arm had been being conducted for three days. At admission, the child's condition is severe due to endogenous intoxication, type II respiratory distress by lower obstructive_constrictive type on the background of pneumonia, anemic, hypoproteinemic and dyselectrolytemic syndroms, and coagulopathy. Given the signs of increasing respiratory distress, hemorrhagic, anemic syndromes, and cerebral deficit, indurative edema of upper-left extremity with the transition to the neck tracheal intubation with respiratory support using artificial lung ventilation was carried out. Because of progression of upper extremity edema, interference with blood flow, we had to do a fasciotomy and necrectomy. Due to the development of organ dysfunction, two sessions of hyperbaric oxygenation were initiated on the seventh day. On the tenth day because of the progression of purulent endobronchitis an intermediate tracheostomy was held. To regress purulent expectorative component therapeutic bronchoscopy was performed six times. Correction of anemic, hypoalbuminemic syndromes and coagulopathy were provided by the transfusion of washed red blood cells, fresh frozen plasma, 10% solution of albumin. With immunosupportive purpose, intravenous human immunoglobulin was administered (three times 5 ml/kg). On the 17th day of treatment at DAIT the respirator was removed. Tracheostomy decannulation was held on the 24th day. On the 26th day the child was transferred for further treatment to Combustiology Department of regional clinical hospital in Ivano-Frankivsk, where the child was discharged due to satisfactory condition on the 38th day of total stay in hospital.
	
	Key words: sepsis, pneumonia, children.
	
	REFERENCES
1. Kuznetsov VA. 2010. Sovremennaia diagnostika khirurgicheskoho sepsisa. Suchasni medychni tekhnolohii. 1: 59–61.
2. Kursov SV. 2011. Hemodynamichna vidpovid na ridynnu resustsytatsiiu u khvorykh z abdominalnym sepsysom. Meditsyna neotlozhnykh sostoianii. 3(34): 76–85.
3. Pro zatverdzhennia klinichnykh Protocoliv nadannia medychnoi dopomohy pry nevidkladnykh stanakh u ditei na shpytalnomu i doshpytalnomu etapakh. Nakaz MOZ Ukrainy № 437 vid 31.08.2004. http://www.moz.gov.ua.
4. Chernii VІ. 2016. Sepsys. Aktualni aspekty intensyvnoi terapii. Shpytalna khirurhiia. 1(63): 121.
5. Shenoy S, Ganesh A, Rishi A et al. 2011. Dopamine versus norepinephrine in septic shock: a meta-analysis. Critical Care Medicine. 15: 89. https://doi.org/10.1186/cc9509
6. Castellanos-Ortega A, Suberviola B, Garcia-Astudillo LA et al. 2012. Impact of the Surviving Sepsis Campaign protocols on hospital length of stay and mortality in septic shock patients: Results of a three-year followup quasi-experimental study. Critical Care Medicine: 1036–1043.
7. Larsen GY, Mecham N, Greenberg R. 2011. An emergency department septic shock protocol and care guideline for children initiated at triage. Pediatrics. 127: 1585–1592. https://doi.org/10.1542/peds.2010-3513; PMid:21576304
8. Dellinger RP, Levy MM, Rhodes A et al. 2013. Surviving Sepsis Campaign: International Guidelines for Management of Severe Sepsis and Septic Shock: 2012. Critical Care Medicine. 41; 2: 637.
9. Levy MM, Dellinger RP, Townsend SR et al. 2010. Surviving Sepsis Campaign: The Surviving Sepsis Campaign: Results of an international guideline-based performance improvement program targeting severe sepsis. Critical Care Medicine. 38: 367–374. https://doi.org/10.1097/CCM.0b013e3181cb0cdc; PMid:20035219
      
 
 
 
 
 
 