HEALTH OF WOMAN. 2015.9(105):43–46; doi 10.15574/HW.2015.105.43 

Thrombohemorrhagic disorders in patients with giant uterine myomas. Diagnosis, prevention and complex correction. 

Tarabrin O., Gavrychenko D., Shcherbakov S., Mazurenko G., Turenko O., Kirpichnikova K.

Odessa national medical University 

The aim of the study was to reduce perioperative blood loss in patients with giant uterine myoma. As a result of studies have provided evidence that the use of antifibrinolytic therapy as intravenous infusion of tranexamic acid for 30 minutes before the surgery in a dose of 20 mg/kg followed by infusion of 5 mg / kg per hour for the first postoperative day, helped to reduce perioperative blood loss by 29%. Hemoglobin level was higher by 10% (p<0.05), blood loss was lower by 29% (p<0.05), the length of stay in hospital was reduced by 24% (p<0.05) in patients of the second group on the second postoperative day. 

Key words: uterine myoma, blood loss, fibrinolysis. 

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