- Functional and organic pathology of the stomach: the problem of differential diagnosis
Functional and organic pathology of the stomach: the problem of differential diagnosis
SOVREMENNAYA PEDIATRIYA.2016.6(78):99-102; doi 10.15574/SP.2016.78.99
Functional and organic pathology of the stomach: the problem of differential diagnosis
Bobrova V. I.
Bogomolets National Medical University named after, Kiev, Ukraine
The article shows the main clinical and functional patterns of formation of inflammation of the gastric mucosa in children. Comparison of clinical and anamnestic data, objective and instrumental examination of patients with functional dyspepsia and chronic gastritis revealed many similarities established specific clinical manifestations of diseases that were common for both functional and organic disorders of stomach. During endoscopic examination of the stomach, regardless of the age of children and duration of the disease, most patients were revealed erythematous changes of gastric mucosa. Also the results of morphological study revealed the high degree of inflammation of MM with predominantly eosinophilic infiltration are hemocirculatory disorders of gastric mucosa, and in patients with long%term chronic inflammation the lymphocyte infiltration of the lamina propria, stromal fibrosis and focal destruction of the glands were found. The results of bacteriological examination indicates that prolonged disease can change stomach microflora features, that has great influence on forming and clinical picture of chronic gastritis.
Key words: children, chronic gastritis, functional dyspepsia.
REFERENCES
1. Аbaturov AE, Gerasymenko ON, Zavgorodnyaya NYu. 2014. Chronic CagA (+) Helicobacter pylori-associated gastritis in children. Xarkov, S.A.M.: 399.
2. Beketova GV. 2012. Chronic gastroduodenitis in children and adolescents: epidemiology, etiology, pathogenesis, diagnosis. Dytyachyj likar. 6(19): 20—24.
3. Byelousov YuV. 2010. Functional and organic diseases of the stomach and intestine in children: formation mechanisms, diagnostic criteria and principles of correction. Pediatrychna gastroenterologiya i nutriciologiya: Materialy naukovo-praktychnoyi konferenciyi z mizhnarodnoyu uchastyu. 20—21 travnya 2010 roku. Xarkiv: 3—8.
4. Bobrova VI. 2015. Diseases of gastroduodenal children: navchalnyj posibnyk dlya studentiv VNZ MOZ Ukrayiny – Xarkiv, Zoloti storinky: 160.
5. Bobrova VI. 2014. Chronic gastroduodenitis in children. Modern methods of diagnosis, treatment and prevention. Monografiya, Kyyiv, «Medekspert»: 112.
6. Gonchar NV, Sokolova MY. 2010. A look at the problem of chronic gastroduodenitis in children 30 years later. Pediatrychna gastroenterologiya i nutriciologiya: Materialy naukovo-praktychnoyi konferenciyi z mizhnarodnoyu uchastyu. 20—21 travnya 2010 roku. Xarkiv: 126-127.
7. Majdannyk VG, Kornejchuk VV, Xajtovych NV, Saltikova GV. 2008. Diseases of the esophagus, stomach and duodenum in children. K,VB «Avanpost-Prym»: 432.
8. Majdannyk VG. 2007. Rome criteria III (2006) diagnosis of functional gastrointestinal disorders in children. Pediatr, akush ta ginekol. 3(5): 13.
9. Nykyforova EM, Alferova VV, Solovyov EN. 2010 The course of chronic superficial gastroduodenitis in children. Aktualnie problemi abdomynalnoj patologyy u detej: Materyali XVII Mezhdunarodnogo Kongressa detskyx gastroenterologov Rossyy y stran SNG. 10—12 marta 2010 g. Moskva: 90—91.
10. Novykova V.P. Features of chronic gastritis at different ages. Gastroэnterologyya Sankt-Peterburga. SPb., 2009; 2-3: 61.
11. Savyczkaya EV, Dolgaya OV. 2008. Functional dyspepsia and chronic gastroverification of the diagnosis. Probl suchasnoyi med nauky ta osvity. 2: 80—82.
12. Deanne LV, Crock, Patricia, Braye, Stephen. 2008. Autoimmune gastritis and parietal cell reactivity in two children with abnormal intestinal permeability. European journal of pediatrics. 167(8): 917—925. https://doi.org/10.1007/s00431-007-0664-z; PMid:18214536
13. Boukthir S, Aouididi F, Mazigh Mrad S. 2007. Chronic gastritis in children. Tunis Med. 85: 756—760.
14. Gottrand F. 2011. Abdominal pain and gastritis in children Rev Prat. J Pediatr Gastroenterol Nutr. 61(5): 639—42.
15. Yanyi Zhang, Xi Yang, Weizhong Gu et al. 2012. Histological features of the gastric mucosa in children with primary bile reflux gastritis. World Journal of Surgical Oncology. 10: 1186. https://doi.org/10.1186/1477-7819-10-27; PMid:22289498 PMCid:PMC3278363
16. Ko Huaibin M, Morotti R, Yershov O. 2013. Eosinophilic Gastritis in Children: Clinicopathological Correlation, Disease Course, and Response to Therapy. Gastroenterology. S-493.
17. McHugh. J, Gopal Purva. 2013. The clinical significance of focally enhanced gastritis in children. The American journal of surgical pathology. 201337(2): 295—299.