HEALTH OF WOMAN.2015.5(101):55–58; doi 10.15574/HW.2015.101.55
 

The uterine leiomyoma – algorithms for the management of women of reproductive age
 

Zaporozhchenko M. B.

Odessa national medical University
 

The work Purpose was to improve algorithm of conducting patients with leiomyoma of uterus. 354 women with leiomyoma of uterus are surveyed. Treatment-and-prophylactic actions were made accordingly the clinical reports confirmed by orders MOZ of Ukraine. Detailed history of patients collected, laboratory and instrumental examination and hardware, morfogistological and immunohistochemical markers of endometrial defined antigens CD34, Ki-67, CD45, б-SMA was held. Algorithm for the management of patients with uterine leiomyoma improved. Accounting for multiple etiologic factors and pathogenic mechanisms of the formation of a benign tumor is a major landmark in the definition of an integrated combined treatment of uterine leiomyoma. Approach to the selection of treatment and preventive measures should be purely individual and pathogenesis warranted by the individual characteristics of the women at the molecular genetic level, baseline assessment of her body (genetic predisposition, the presence of concomitant extragenital, generative characteristics, reproductive functions, patient age, clinical uterine form). Medication, and in the absence of effect – myomectomy shows in patients with uterine leiomyoma simple when planning pregnancy. Possible options of the treatment of patients with uterine leiomyoma proliferative type: conservative treatment, surgery, medical therapy in combination with surgical treatment of uterine fibroids, uterine artery embolization, each of which has its own strict indications, in the absence of oncological process.
 

Key words: management algorithm, uterine leiomyoma.
 

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