PERINATOLOGIYA I PEDIATRIYA.2015.3(63):59-62; doi 10.15574/PP.2015.63.59 
 

Estimation of the functional condition of the nervous-muscle system in children with juvenile rheumatoid arthritis and clinical signs of secondary myopathy 
 

Dudnyk V. M., Bereznyckyi О. V., Vyzhga Yu. V.

Vinnytsya national medical university, Vinnytsya, Ukraine 
 

Purpose — to estimate functional condition of the nervous_muscle system in children with juvenile rheumatoid arthritis and clinical signs of secondary myopathy. 
 

Patients and methods. Under the control we passed examination of 72 children with juvenile rheumatoid arthritis that were on the treatment course in Vinnytsya regional children's hospital. The average age of the patients was 11.3 (8.6; 15.2) years. The first group was presented with 43 (68.06±4.16%) patients with juvenile rheumatoid arthritis with clinical signs of the secondary myopathy. The second group included 29 (40.28±4.16%) patients with juvenile rheumatoid arthritis without such clinical symptoms. 
 

Results. Clinical presentation of the secondary myopathy are common for the patients with monoarthritis (58.14±2.87%), moderate activity of the disease (41.86±4.08%) and functional insufficiency (62.79±3.96%). For the patients with juvenile rheumatoid arthritis is common decreasing of the amount of the muscle fibres with the next development of the degenerative process that followed with decreasing of the amplitude (on 21.86±2.27%) and frequency of the muscle constructions (on 55.86±2.89%) according to electroneuromyography data. 
 

Conclusion. Perspective is further investigations of the pathogenetic moments of the secondary myopathy origin in patients with JRA and its correlation with main clinical and laboratory signs of the activity of the process with the aim of modification of the next treatment steps. 
 

Key words: secondary myopathy, juvenile rheumatoid myopathy. 
 

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