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Contents of toxic elements in biological environment of pregnant women of all reproductive age give birth first time 

PERINATOLOGIYA I PEDIATRIYA. 2016.3(67):72-75; doi 10.15574/PP.2016.67.72 
 

Contents of toxic elements in biological environment of pregnant women of all reproductive age give birth first time 
 

Markevych V. V.

Shupyk National Medical Academy of Postgraduate Education, Kyiv, Ukraine 
 

Purpose — to investigate the toxic contents of microelements in serum and erythrocytes of pregnant women in the early, middle and old reproductive age in the case of the first delivery.


Patients and methods. The study was conducted in the third trimester of pregnancy on 36.08±0.59 weeks of gestation. Reproductive age of pregnant women

was 16.33±0.21, 24.67±0.37 and 36.14±0.77 years respectively. The content of toxic ME (chromium, nickel, lead and cobalt) in the biological substrates was determined by atomic absorption spectrophotometer C — 115 MI.


Results. We found that pregnant women regardless of reproductive age who gave birth for the first time had high level of nickel both in serum and in red blood cells. With the growth of reproductive age we saw accumulation of toxic chromium in serum. Much less content of cadmium in red blood cells and possibly other tissues in pregnant women of older reproductive age apparently linked to the more conscious and responsible attitude to their health condition, the process of pregnancy and a healthy lifestyle and above except the main source of cadmium — smoking. The lowest content of lead in red blood cells is determined in the women of middle reproductive age. At the same time serum and erythrocytic content of lead in any group was not higher its level in healthy pregnant women.


Conclusion. Nowadays very actual is researching of placenta as a body that provides trace element balance in system «mother—placenta—fetus». To determine the role of placenta in protecting the fetus from exposure of toxic elements reasonable is investigation of their content in the placenta and its functions — barrier penetration, depositing of essential and toxic elements.


Key words: toxic elements, pregnant women, reproductive age, first birth.


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