Modern Pediatrics. Ukraine. (2025).7(151): 6-13. doi: 10.15574/SP.2025.7(151).613
Gevkaliuk N. O., Martyts Y. M., Mykhailiuk V. M.
Ivan Horbachevsky Ternopil National Medical University, Ukraine

For citation: Gevkaliuk NO, Martyts YM, Mykhailiuk VM. (2025). Analysis of the functional activity of salivary glands in children with influenza and other respiratory viral infections. Modern Pediatrics. Ukraine. 7(151): 6-13. doi: 10.15574/SP.2025.7(151).613.
Article received: Jun 16, 2025. Accepted for publication: Nov 09, 2025.

Acute respiratory viral infections (ARVI) occupy the first place in the structure of children's infections. Rashes on the mucous membranes in the oral cavity reflect the patterns of the infectious process as a whole.
Aim – to is aimed at evaluating the secretory function of salivary glands, physico-chemical, and morpho-structural features of oral fluid in different forms of severity of influenza stomatitis in children.
Materials and methods. The rate of salivation in 318 children with ARVI lesions of the oral cavity was performed on an empty stomach without stimulation in graduated tubes to further morphological examination. Qualitative analysis of secretion was determined visually. Determination of the viscosity was performed on a capillary viscometer Oswald; the buffer capacity was determined as described Krasse, the pH was determined, and crystalography of oral fluid was conducted. The research on the secretory function of salivary glands was conducted by sialometri method.
Results. The rate of salivation in patients with acute viral stomatitis caused by the influenza virus decreased with increasing severity of disease in severe ARVI 3.17 times compared to children in the control group. Counting the functioning of minor salivary glands showed their reduction to 11.46±0.14 with severe acute viral stomatitis. The qualitative analysis showed that salivary gland secretions increase their viscosity and the presence of visible inclusions. Determination of the pH of the oral fluid showed a shift to the acidic side. The buffer capacity is directly dependent on the rate of salivation and pH. The nature of changes in the crystals of the oral fluid is determined by the severity of lesions of the oral mucosa.
Conclusions. Changes in physico-chemical properties, acid-salt metabolism, morpho-texture pecularities, changes in the crystals of oral fluid occurring against the background of hiposalivation show a decrease in functional activity of salivary glands in ARVI in children with disease manifestations in the oral cavity.
The research was carried out in accordance with the principles of the Declaration of Helsinki. The study protocol was approved by the Local Bioethics Commission of an institution. For each child, the informed consent of their mother to participate in the study was obtained.
The authors declare no conflict of interest.
Keywords: mucous membrane, pathological bites, occlusion, oral fluid, crystallogram, hyposalivation, acute respiratory viral infections (ARVI).

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