Modern Pediatrics. Ukraine. (2025).5(149): 125-131. doi: 10.15574/SP.2025.5(149).125131
Kryuchko T. O., Shcherbak V. V., Nesina I. M., Oliinichenko M. O., Lytus S. I.
Poltava State Medical University, Ukraine

For citation: Kryuchko TO, Shcherbak VV, Nesina IM, Oliinichenko MO, Lytus SI. (2025). Food protein induced proctocolitis syndrome in infants (clinical case). Modern Pediatrics. Ukraine. 5(149): 125-131. doi: 10.15574/SP.2025.5(149).125131.
Article received: Apr 04, 2025. Accepted for publication: Sep 10, 2025.

Food protein-induced allergic proctocolitis is a transient cell-mediated inflammatory disease of the colon that manifests as haemocolitis, often accompanied by mucous streaked faeces. This allergopathology is determined on the basis of the disappearance of symptoms after the exclusion of a food allergen, most often cow's milk protein, from the child's diet.
Аim – to report a clinical case of proctocolitis syndrome induced by food proteins, as well as to conduct a modern analysis of the main aspects of diagnosis, differential diagnosis and management of this disease.
The article presents a clinical observation of a child of infancy, who had progression of the disease due to non-compliance with elimination therapy therapy and dietary disorders on the part of both the mother and the child due to continued consumption of dairy products. The main aspects of timely verification, differential diagnosis and management of this allergopathology are also considered, despite the low prevalence of the disease, which emphasises the relevance of early detection and a comprehensive approach to treatment, taking into account modern international recommendations.
Conclusions. Food protein-induced allergic proctocolitis is an important problem in paediatric gastroenterology, particularly at the primary care stage, which requires a correct and timely approach to patient management. Effective treatment and monitoring is possible only with close cooperation between paediatricians, general practitioners, gastroenterologists and allergists.
The study was conducted in accordance with the principles of the Declaration of Helsinki. Informed consent was obtained from all participants.
The authors declare no conflict of interest.
Keywords: allergic proctocolitis, food protein-induced, allergy, cow's milk protein, haematochezia, diagnosis, treatment, elimination diet, children.

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