- The impact of various forms of b-thalassemia in the physical development of girls and women
The impact of various forms of b-thalassemia in the physical development of girls and women
HEALTH OF WOMAN. 2016.1(107):142–145
The impact of various forms of b-thalassemia in the physical development of girls and women
Djabrailova F. Q., Abbasova F. Y., Aliyeva E. M., Aliyeva N. Sh.
Azerbaijan Medical University, Baku
Purpose of the study: The purpose of research to study the features of physical development of girls and women in various forms of b-thalassemia.
Material and methods. Surveyed 83 girls and women of various forms of b-thalassemia in the active reproductive period. In 53% of patients had great form, 19.3% – intermediate, 18.1% – small form of thalassemia. In 9.6% of patients have an anomalous form of b-talassemia. To determine the physical development measured the following anthropometric indices: increase of body, mass of body, arm span, length of legs, shoulder width, chest circumference. Measured as the outer dimensions of the pelvis.
Results. As a result of the study, it was found that patients with major, intermediate and abnormal forms of thalassemia had marked delayed physical development.
With a small form of thalassemia physical development correspond to physiological fluctuations.
Conclusion. Patients with b-thalassemia are at high risk of physical development delay.
Key words: thalassemia, major, intermediate, minor forms of b-thalassemia, delay in physical development.
REFERENCES
1. Akerly KR, Aliyeva EM 2014. Features of girl`s physical development with amenorrhea in the early reproductive period. Medicine, Kazakhstan. 8:68-71.
2. Lochmatow, M E., Smetanina N With, Finogenova N And. 2009. Epidemiology of haemoglobin disorders in Moscow. Pediatrics 87;4:46-50.
3. Galanello R, Origa R 2010. Beta-thalassemia. Ophanet Journal of Rare Diseases 5:11. http://dx.doi.org/10.1186/1750-1172-5-11; PMid:20492708 PMCid:PMC2893117
4. Karimi M, Cohan N, Parand S 2015. Thalassemia and Women’s Health. Women’s Health Bull. 2;3:2944–2950. http://dx.doi.org/10.17795/whb-29440
5. Modell B, Darlison M 2008. Global epidemiology of haemoglobin disorder and derived service indicators. Bull World Health Organ. 86:840–844. http://dx.doi.org/10.2471/blt.06.036673
6. Panigrahi I, Marwaha RK, Kulkarni K 2009. The expanding spectrum of thalassemia intermedia. Hematology 14;6:311–314. http://dx.doi.org/10.1179/102453309X12473408860307; PMid:19941736
7. Richardson M. 2007. Microcytic anemia. Pediatr Rev. 28;1:5–14. http://dx.doi.org/10.1542/pir.28-1-5
8. Qazi R.A, Shams R, Hassan H, Asif N 2014. Screening for Beta Thalassemia trait. J.Rawalpindi Medical College (JRMC) 18;1:158–160.
9. Siew Leng Kho, Kek Heng Chua. 2013. The molecular confirmation of Beta Thalassaemia mutations. J. Seasors. 13:2506–2514.
10. Thein SL 2008. Genetic counseling of the Beta thalesemia trait. Br.J.Haematol. 141:357–366. http://dx.doi.org/10.1111/j.1365-2141.2008.07084.x; PMid:18410570
11. Weatherall DJ 2008. Hemoglobinopathies worldwide: present and future. Curr Mol.Med. 8:592–599. http://dx.doi.org/10.2174/156652408786241375; PMid:18991645
