HEALTH OF WOMAN. 2016.1(107):103–106 
 

Effect of preventive and medical care on selected homeostasis indicators in women with the risk of post-term pregnancy 
 

Butkova O., Zhabchenko I., Lishchenko I., Tishchenko V., Kovalenko T., Bondarenko E., Strizhak S.

SI «Institute of Pediatrics, Obstetrics and Gynecology, NAMS of Ukraine», Kiev 
 

The Aim of Research. Еstimation of the preventive measures impact on some biochemical tests in women for prolonged pregnancy risk groupe before delivery. 
 

Materials and Methods. The concentrations of magnesium and calcium in blood serum were investigated, as well as thermal stability and acid serum proteins in 61 pregnant women in 39–40 weeks of pregnancy. First group was formed by 25 pregnant women with risk of pregnancy prolongation who received the recommended range of treatment, the second one was formed by 22 women at risk of pregnancy prolongation who did not receive special treatment. The control (group 3) was formed by 14 women with full-term pregnancy at 39-40 weeks of gestation with timely maturation of the cervix and physiological pregnancy. Determining the readiness of the cervix for childbirth was performed using rapid test «Actim Partus» in the period 39–40 weeks. Determining the level of magnesium and calcium in blood serum was conducted using photometric method sets BIOLATEST company LACHEMA (Czech Republic). Determination of acid resistance of nuclear acids and proteins termal denaturation factions in blood serum was conducted using B.A. Roytruba’s method. 
 

Results. The results suggest that calcium and magnesium concentration in blood serum in all pregnant women was almost the same. The content of asid-persistent proteins in the serum of pregnant women from the first group increased by 20% compared to the concentration in third groupe women, while the index of acid persistent proteins in pregnant women from the second groups did not differ from the third group ones. The least pronounced changes in temperature influence on the structure of proteins in blood serum were observed in first group of women that were shown only at 320 nm. A wide range of termal denaturation was registered in the second grope pregnant (260–350 nm). The results of rapid cervical preparation test showed the in time preparation in women of the first grope 69,7% against 51,5% from the second one.

Conclusion: health-care complex, which was hold on the women from the first grope, has a positive impact on adaptation properties of some proteins in the blood serum of women at pregnancy prolongation risk grope, that gave chance to give birth to healthy newborns in 87% of women. 
 

Key words: pregnancy, prevention, post-term pregnancy, biochemical parameters. 
 

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