HEALTH OF WOMAN. 2016.5(111):87–90; doi 10.15574/HW.2016.111.87 
 

Preventive maintenance perinatal pathologies at women with anomalies of development of uterus

Sazonov M. A.

Shupyk National Medical Academy of Postgraduate Education, Kiev, Ukraine

The objective: frequency decrease perinatal pathologies at women with anomalies of development of uterus on the basis of studying clinical-ehografical, endocrinological, dopplerometrical, cardiotokografical and morphological researches, and also improvement of algorithm treatment-and-prophylactic and forecasting actions.

Patients and methods. It is spent twostages research in which result it is created two information files. The first included results of the retrospective analysis of the medical documentation of pregnant women with anomalies of development of uterus of vertical type from 2003 on 2012 (150 stories of sorts and development of newborns) for studying of features of current of pregnancy and perinatal results, and also working out of optimum technologies of supervision and delivery patients – 1 – the basic retrospective group. At the second stage of researches spent supervision from early terms of pregnancy of 40 women with anomalies of development of uterus which have made 2 – the basic prospective group (2013–2015), and also 30 patients with normal anatomy of internal genitals at which was not burdened obstetrical anamnesis, surveyed in the same terms and on the same parametres which have made 3 – control group. In a complex of the spent researches have been included clinical, ehografical, dopplerometrical, cardiotokografical, endocrinological, microbiological, morphological and statistical.

Results. Perinatal outcomes of delivery of women with uterine APM characterized by a high rate of perinatal losses (40.0±4.0 ‰) respiratory distress syndrome (13.3±2.8%); delay the development of the fetus to malnutrition (28.0±3.7%); various forms of neonatal asphyxia (54.0±4.1%), especially severe forms of (10.0±2.5%). The most concerning adverse perinatal outcomes is a two-horned uterus with the merger of horns in the middle third; intrauterine septum and unicorn uterus. Using advanced algorithm therapeutic and preventive and predictive measures can reduce the incidence of preterm birth (from 24.0±3.5% to 7.9±4.4%); developmental delays and malnutrition of the fetus (from 28.0±3.7% to 13.2±5.5%); asphyxia of varying severity (from 54.0±4.1% to 34.4±8.4%), as well as perinatal losses (from 40.0±4.0 ‰ to 25.0±2.5 ‰).

Conclusion. Results of the spent researches testify that women with various anomalies of development of uterus make group of high risk on development of placentary dysfunction and the subsequent perinatal pathologies. Use of the algorithm improved by us forecasting and treatment-and-prophylactic actions mother-placenta-born allows to lower essentially frequency of infringements of functional condition of system, and also to improve perinatal results of delivery.

Key words: anomalies of development of uterus, perinatal pathology, preventive maintenance.

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