Modern pediatrics. Ukraine. 2019.4(100):33-37; doi 10.15574/SP.2019.100.33

Vlasova O. V., Bezrukov L. O., Koloskova О. К.
HSEЕ «Bukovinian State Medical University», Chernivtsi, Ukraine

For citation: Vlasova OV, Bezrukov LO, Koloskova ОК. (2019). Clinical and epidemiological analysis of maternal factors of propensity to neonatal sepsis under conditions of different environmental impact. Modern pediatrics. Ukraine. 4(100): 33-37. doi 10.15574/SP.2019.100.33
Article received: Dec 29, 2018. Accepted for publication: Apr 18, 2019.

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Objective. To improve the results of diagnosis and treatment of neonatal sepsis, to study the peculiarities of maternal predisposition factors to its development in contrast to the ecological characteristics of the regions of residence of pregnant women.

Materials and methods. Clinical and epidemiological analysis of the influence of maternal predisposition factors on the formation of neonatal sepsis in 260 newborns, has been conducted, which depends on the environmental characteristics of the places of residence of pregnant women.

Results. It has been shown that in case of the absence of significant differences in the indicators of reproductive health, as well as somatic pathology and obstetric and gynecological history, the dwelling of pregnant women in unfavorable conditions is accompanied by the increased risk of miscarriage and the birth of children in the gestation period to 35 weeks (HS=2.04; 95% CI 1.2–3.7), the birth of children with extremely low body weight (HS=2.9; 95% CI 1.1–7.3), as well as probably lower Apgar score on the 5th minute of a newborn's life (HS=5.12, 95% D 2,1–12,6).

Conclusions. The change can be regarded as a consequence of chronic contact of pregnant women with the pollution areas of their residence.

The research was carried out in accordance with the principles of the Helsinki Declaration. The study protocol was approved by the Local Ethics Committee (LEC) of institution. The informed consent of the patient was obtained for conducting the studies.

No conflict of interest was declared by the authors

Key words: neonatal sepsis, risk factors, maternal predisposition factors, pollution areas.

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