HEALTH OF WOMAN. 2019.1(137):82–86; doi 10.15574/HW.2019.137.82

Dyndar O. A.
Bogomolets National Medical University, Kiev

The objective: to determine the efficacy and safety of the “Magnefar B₆” application in pregnant women in the aspect of obstetric and perinatal complications frequency reduction.

Materials and methods. The examination of 60 women in the second half of pregnancy was conducted. A study group consisted of 30 pregnant women who in order to prevent obstetric and perinatal complications obtained «Magnefar B₆» in the second half of pregnancy. The group of comparison was formed by 30 pregnant women who did not take any magnesium drugs. Magnesium deficiency symptoms were determined with the help of questionnaire. The clinical course of the second half of pregnancy, delivery, postpartum period, fetal and newborn status were analyzed with the determination of the frequency and structure of obstetric and perinatal complications.

Results. Questionnaire survey which was conducted by pregnant women of the main and comparative groups at 24–26 weeks, revealed symptoms of magnesium deficiency in 86,6% of cases. After the correction with the help of «Magnefar B₆» in the main group of pregnant women there was a significant improvement in wellbeing and a decrease in the frequency and severity of magnesium deficiency. However, the increase of gestation period was coupled with the increase of pregnant women with magnesium deficiency symptoms, which had a negative impact on the course of pregnancy, delivery, the postpartum period, the state of the fetus and newborn. The main complications were: the threat of premature delivery, preeclampsia, anemia, placental dysfunction, symptoms of respiratory viral infection, extragenital pathology aggravation, gestational diabetes, premature rupture of membranes, abnormalities of labor, fetal distress, placental tissue defect, episio-/perineotomy. The postpartum period was complicated by the divergence of the perineal sutures, uterus subinvolution, thrombophlebitis of the superficial veins of the lower extremities, infiltration of the postoperative suture, postpartum endometritis, hemorrhoids. Complications of the newborn condition were: asphyxia, respiratory distress syndrome, the implementation of intrauterine infection, posthepatic encephalopathy.

Conclusion. The correction of magnesium deficiency with the help of «Magnefar B₆» provided a reduction in the frequency and severity of complications of pregnancy, delivery, postpartum period, improving the condition of the fetus and newborn.

Key words: magnesium deficiency, obstetric and perinatal complications, Magnefar B₆.

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