HEALTH OF WOMAN. 2019.1(137):55–59; doi 10.15574/HW.2019.137.55

Fedorych P. V., Mavrov G. I., Podolsky Vl. V.
Ukrainian Military Medical Academy, Kyiv
SI «Institute of Dermatology and Venereology, NAMS of Ukraine», Kharkiv/
SI «Institute of Pediatrics, Obstetrics and Gynecology named after Academician O.M. Lukyanova», Kyiv

The objective: to substantiate the use of the antimicrobial drug Doramycin (spiramycin) in the treatment of bacterial vaginosis (BV), taking into account the sensitivity to it of the individual components of the polyetiological disease.

Materials and methods. Using the real-time polymerase chain reaction method, a DT-96 amplificator using the Femoflor-16 reagent kit was used to examine 71 patients with chronic inflammation of the genitourinary system, in whom microorganisms associated with BV were detected. The sensitivity of the detected microflora to Doromycin has been analyzed.

Results. The overwhelming majority of microorganisms and / or groups of microorganisms (sensitivity to part of the constituent groups) associated with BV, which can be detected using the Femoflor-16 reagent kit, has been shown to be sensitive to Doramycin.

Conclusion. Doramycin is advisable to use as a drug of choice for the comprehensive treatment of bacterial vaginosis in women, as well as anaerobic and microaerophilic dysbiosis of the urinary system of men. The main additional benefits of Doromycin are the possibility of prescribing the drug during pregnancy, as well as the possibility of simultaneous eradication of both certain causative agents of bacterial vaginosis, and Chlamydia trachomatis and Ureaplasma urealyticum, the most common causative agents of inflammation of the genitourinary system today.

Key words: Doramycin, spiramycin, bacterial vaginosis, treatment, Femoflor-16 reagent kit.

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