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- Sovremennaya Pediatriya
- SOVREMENNAYA PEDIATRIYA № 3 – 2012
SOVREMENNAYA PEDIATRIYA № 3 – 2012
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Read online Новый календарь прививок в Украине: современные возможности иммунопрофилактики.
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Dedyshyn L. P.
Education of physicians on clinical pediatrics under the principles of Bologna declaration.
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Summary. The article describes main challenges being raised during implementation of credit-module approach in organization of education process for physicians at the department of paediatrics. Using an experience gained from the preceding programs, present clinical facilities and available backing-up of the educational process, the department attempts to solve the rising challenges and secure high quality education for specialists.
Key words: education process, credit-module approach, pediatria.
Possner Mike
Allergyprevention with the use of moderate serum hydrolysate.
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Summary. The advantages of the mixture «NAN® Hypoallergenic» based on a moderate protein hydrolyzate in children who are on the bottle-feeding are shown. Good tolerability and preventive action of the mixture for atopic dermatitis in infants with allergy in the family history is proved, in numerous and lengthy investigations. «NAN® Hypoallergenic» reduces the risk of atopic dermatitis during the first year of life by approximately 50%, preventive effect persists up to 5-6 years.
Keywords: baby, bottle feeding, atopic dermatitis, prevention, with a mild mixture of protein hydrolysis, NAN® Hypoallergenic.
Sakalosh L. P., Kvit D. I., Stasyna Yu. V., Sakalosh A. V., Marchenko T. Z., Semenyuk O. O.
Holt—Orama syndrome: clinical case.
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Summary. A came of Holt—Orama syndrome in a daby of 2,5 yeur old: additional falangii of the first fingers of brushes, a defect is between an auricle partition, an aortic channel is opened.
Key words: children, malformation, diagnostics, therapy.
Nedelskaya S. N., Ruskina E. V.
Evolution in the treatment of bronchial asthma in children.
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Summary. In the article the features of the course and selection of therapy in children with asthma are shown; the questions of achieving control of allergic inflammation are carried out.
Key words: asthma, children, therapy, control.
Marushko Yu. V., Gracheva M. G.
Current state of the problem of helminthiasis in children. The questions of diagnosis and treatment.
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Summary. The data on the prevalence of helminthes infections in the world is presented; the clinical manifestations, complications, principles of diagnosis and treatment of helminthes infections in children and adults are shown.
Key words: Helminthiasis, diagnosis, treatment.
Frolova T. V., Okchapkina O. V., Berus A. V., Dubonosov V. L.
Mineral predictors of vegetative dysfunction formation in schoolchildren.
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Summary. Results of 5 years longed study of schoolchildren with vegetative dysfunction and unidentified connective tissue dysplasia were displayed in the work. Mineral predictors of formation of different kinds of vegetative dysfunction were determined in children with fibrillogenesis disfunction. Profilaxis mesures were also worked out.
Key words: сhildren, vegetative dysfunction, mineral content.
Козачук В. Г.
Пальмовое масло в детском питании.
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Lezhenko G. A., Usachova E. V., Paholchuk T. N., Silina E. A., Matveeva T. B.
Experience of use Cefixime® cephalosporin of the III generation in the treatment of salmonellosis in children.
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Summary. On the basis of a dynamic clinical and laboratory monitoring of 57 children with salmonellosis of different age groups show the effectiveness of antibiotic Cefixime® is shown.
Key words: Salmonellosis, children, treatment, Cefixime®, Riabal®.
Romanenko T. A., Kolesnikova I. P.
Analisis of influence of pertussis pathogen circulating on the morbidity dynamics in the children of different age.
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Summary. Exploration of the prevalence of different types Bordetella and the incidence of whooping cough persons of all ages showed correlation of these processes. A mathematical model to predict trends of disease based on the assessment activity circulating serological variants of the pathogen made.
Key words: pertussis, incidence, serological types of pathogen, correlation.
Moroz G. I., Vidiboretc S. V.
Acquired haemophilia in pediatrics.
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Summary. The basic questions of etiology, pathogenesis, clinic, diagnostics and treatment of the acquired haemophilia, rare, but potentially dangerous for life hemorragic disease, which arises up because of development of autoantibodies, directed against the plasma coagulation factors are presented in the article. Diagnostic of acquired haemophilia is a major problem in children because this rare disorder is not well-recognised in general medicine and paediatrics
Key words: acquired hemophilia, autoantibodies, bleeding, factor VIII, immunosupression, inhibitor.
Fesenko M. E., Melashchenko E. I.
The morbidity, physical and neuro-psychic development children with congenital cytomegalovirus infection.
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Summary. Presented results of the follow-up of 58 children, given birth from mothers with CMV infection, in current two years to lifes. Was studied the disease, physical and nervously-psychic development of the examined children, were conducted medical-rehabilitation actions for the reason preventive maintenances of the shaping recurring and chronic pathologists.
Key words: morbidity, nervously-psychic development, congenital cytomegalo-virus infection.
Boyko Yа. Ye., Chernyshov V. P.
Biologic therapy of juvenile rheumatoid arthritis: from theory to practice. First experience of adalimumab in patients with juvenile rheumatoid arthritis.
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Summary. The use of biological drugs in clinical rheumatology has a significant effect on therapeutic paradigm of juvenile rheumatoid arthritis. In this paper we analyzed the global experience of using biological drugs to patients with JRA and present the first results of treating patients, who are refractory to the basic therapy of JRA with adalimumab.
Key words: Juvenile Rheumatoid Arthritis, biological drugs, adalimumab.
Mukvich E. N., Zadorozhnaya T. D., Poluk T. A., Ludwik T. A.
Juvenile idiopathic arthritis and immunopathological role of disorders of intestinal microbiota.
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Summary. The article provides the results of experimental, morphological and clinical-paraclinical researches, which shown the role of breach of the intestinal microflora in patients with juvenile rheumatoid arthritis. Including of probiotic microflora in complex therapy was proposed.
Keys words: rheumatoid arthritis, intestinal microflora, children, multiprobiotic.
Starets E. A., Fedorenko O. V.
Results of multifactor analysis of clinic-paraclinical parameters in children with acute infectious myocarditis.
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Summary. Clinical and laboratory parameters in children with acute infectious myocarditis were studied in the article. Found that the use of multivariate correlation analysis of clinical and instrumental data of acute infectious myocarditis in children makes it possible to predict the severity of the disease.
Key words: children, acute infectious myocarditis, multifactor correlation analysis.
Glyadelova N. P., Kozachuk V. G., Korolyova V. A., Loboda R. N., Shurygina I. V.
The use of the 2nd generationcephalosporinsin the therapy ofpharyngotonsillitis in children.
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Summary. Adequate and effective antibiotic therapy of tonsillitis (pharingotonsilitis) is one of the major problems of Pediatrics and Pediatric Otolaryngology, representing the great practical interest for physicians of many specialties. In the article the modern data of etiology, approaches to the appointment of antimicrobial therapy for children with pharingotonsilitisis summarized. Particular attention is paid to cefuroximeaxetilthe antibiotic of cephalosporin groupof the II generation, its efficacy in the treatment of chronic pharingotonsilitis in the period of exacerbation.
Key words: children, tonsillitis, pharingotonsilitis, antibiotic therapy, cefuroxime axsetil, Zinnat™.
Starets E. A., Fedchuk I. N., Stabetskaya S. A.
Efficacy and safety of ormaks for the treatment of acute simple bronchitis in infants.
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Summary. In the article the data of the efficacy and safety of the Ormaks preparation for the treatment of acute simple bronchitis in children from the standpoint of evidence-based medicine is carried out. According to the data of a cohort prospective study, the average duration of the treatment by Ormaks was significantly shorter than treatment by the preparation of other groups — the main clinical manifestations of the disease were stopped during the three-day course of treatment. Also,Ormaks demonstrated sufficient security in the current study.
Key words: children, acute simple bronchitis, antibiotic therapy.
Duka K. D., Ilchenko S. I., Duka I. G.
Modern aspects of chronic bronchial inflammation in childhood and ways to prevent.
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Summary. The results of the research, presented the concept on the role of specific risk factors (including bronchopulmonary dysplasia, active and passive smoking, the propensity to pneumofibrosis, energy-deficit states, disbiotical disorders of microflora of medium and lower respiratory tract, dyskinesia of respiratory muscles) in the development of chronic inflammation in bronchus and formation of chronic bronchitis due to violation of the metabolic and drainage functions of respiratory system. Given this concept, the effective diagnostic methods and prevention circuitry of irreversible changes in bronchus with the appointment of preparations with antioxidative and metabolic activities were proposed.
Key words: children, adolescents, chronic bronchitis, bronchopulmonary dysplasia, prediction, prevention.
Marushko T. V.
The role of elimination therapy in the treatment of allergic rhinitis in children.
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Summary. The article presents the literature evidence about the importance of elimination therapy for diseases of the nose and paranasal sinuses in children. We consider separately the question of the use of irrigation therapy with No-Sol in children with allergic rhinitis.
Key words: diseases of the nose and paranasal sinuses, allergic rhinitis, irrigation therapy, No-Sol.
Okhotnikova E. N., Mellina K. V., Bondarenko L. V., Pappa I. V.
Place of modern enterosorption in the treatment of children with allergic dermatosis.
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Summary. The experience of the use of preparation «Atoxil» in the treatment of allergic diseases (urticaria, atopic dermatitis) in children is shown. EnterosorbentAtoxil has established itself as an effective and important component in the complex treatment of alimentary dependent allergic pathology. The application of Atoxilallows reducing the duration of the acute period of blood pressure, urticaria and angioedema in children and reducing the dose of systemic corticosteroids coursework.
Keywords: allergic diseases, complex therapy, chelators, Atoxil.
Tsodikova O. A., Garbar K. B., Barchan G. S.
Sanogenetic correction of mucosal immunity in children with the use of modern phytoimmunomodulators.
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Summary. In the case of children with recurrent respiratory infections the multidirectional nature of the content of the oscillations of the secretory immunoglobulin A (Sig A) in the saliva is demonstrated, depending on the type of general nonspecific adaptive reactionsof the body, which dictates the need-based approach to the appointment of causal treatment and immunorehabilitation. The dynamics of Sig A level in saliva in the treatment process allowed estimating the efficiency of phytoimmunopreparation «Imupret» in the complex of rehabilitation measures, that point on inclusion of sanogenesis mechanisms at it use in children: elimination of inflammatory and allergic processes, reduction of endogenous intoxication and autonomic disorders.
Key words: mucosal immunity, adaptive response.
Aryaev N. L., Bredeleva N. K., Vasilchenko L. V., Ignatenko M. I., Ignatenko A. S.
Experience of use of Mutaflora for immunity enhance in premature infants.
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Summary. The efficiency of application of the probiotic Mutaflor for increase immunity was studied in 30 preterm newborns. The decrease of the risk of the acute respiratory infections and pneumonias during the 1 st of life in preterm infants has been proved. Mutaflor demonstrates good individual bearableness and low frequency of side effects.
Key words: probiotic, Mutaflor, preterm newborns.
Lezhenko G. A., Pashkova E. E., Pantushenko L. I.
Proving of decision of treatment tactics of acute sinusitis in children.
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Summary. Analysis of efficiency of oral administration of antibiotic Cefodox (cefpodoxime proxetil) in treatment of acute bacterial sinusitis in children was traced. It was showed that Cefodox is an effective and safe medicine and can be used in empirical treatment of the suppurative diseases of nasal accessory sinuses in children.
Key words: children, acute sinusitis, Cefodox.
Shadrin O. G., Dyukareva-Bezdenezhnyh S. V., Ostapchuk T. G., Gregul N. A.
Experience of Pikovit syrup use in infants with organic intestinal diseases.
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Summary. In the article there are presented the results of positive experience of Pikovit syrup use secondary to baseline therapy in children aged from 1 to 3 years with diseases of the gastrointestinal tract.
Key words: infants, hypovitaminosis, organic intestinal pathology, Pikovit.
Ermolenko V., Kharitonova L., Yakimova L.
Experience in using ursodeoxycholic acid in children with gallbladder cholesterolosis.
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Summary. The advent of high-resolution ultrasound devices could reveal gallbladder cholesterolosis (GBC) in its early stages and keep track of the specific features of its clinical course. Instead of cholecystectomy (the conventional treatment of GBC), ursodeoxycholic acid has been used in pediatric patients. The findings have confirmed the advantages of medical therapy in children with GBC. An algorithm for managing these patients is proposed.
Key words: gallbladder cholesterolosis, children, ursodeoxycholic acid.
Shadrin O. G., Marushko R. V., Marushko T. L., Tyschenko V. K., Galazjuk L. V.
Treatment modernisation of chronic inflamatory intestinal bowel diseaseses in infants.
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Summary. Done comparative studies in order to research the level of mucin glycoproteins and their derivatives, SIgA and status of intestinal microbiocenosis in fesses samples of children with chronic post-infectious colitis. Proved that the use of functional foods such as multiprobiotics, prebiotics, LC PUFA (omega-3), L-carnitin in the complex therapy of chronic colitis in children of early life, leads to the improvement of status of preepithelial mucous barrier and micribiota in large bowel, restitution of intestinal epitheliocytes, reparation of large bowel mucosa and therapeutic results of the disease treatment.
Key words: chronic post-infectious colitis, children of early life, functional foods, microbiocenosis large bowel.
Kaplina L. I., Kuzmenko I. V., Kozhevin R. V., Bozhko L. I.
Medical nutrition and restoration of water and electrolyte balance for antibiotic-associated diarrhea in children.
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Summary. The clinical trial for children of early age with signs of an antibiotic-associated diarrhea was conducted. We evaluated the dynamics of clinical symptoms and laboratory data on the background of complex treatment with rehydration solutions for restoring fluid and electrolyte balance, and a special milk formula for therapeutic feeding.
Key words: antibiotic-associated diarrhea, early age children, rehydration, therapeutic food.
Marushko Yu. V., Todika Yu. І., Asonov A. O.
Experience of theuse of omeprazol (Omez®, dr. Reddy's) for the tratment of gastroduodenal pathology in clinical pediatric practice (literature review).
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Summary. The article analyzed the world literature on the problem of treatment of gastroduodenal pathology in children using the drug from the group of proton pump inhibitors — omeprazole. High prevalence of gastro-duodenal diseases in childrenof all ages, leads to finding effective and safe therapeutic approach. Omeprazoleis used in children over 1 year, reveals the high efficacy and safety in the treatment of erosive and inflammatory diseases of the esophagus, stomach and duodenum, ezofahal reflux disease, in part antihelicobacter therapy.
Key words: gastro-duodenal pathology, children, omeprazole, helicobacter pylori, proton pump inihbitory.
Belousov Yu. V., Belousova O. Yu.
Is intestinal dysbiosis always secondary?
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Summary. Problems of intestinal dysbiosis pathogenesis in children are discussed. An opinion is advanced that dysbiosis can appear not only in nosological period of disease, but also in premorbid and prenosological periods and it is primary in that case. On the base of intestinal biocenosis researching in inflammatory bowel diseases (chronic nonspecific nonulcerative colitis) and functional bowel diseases (irritated bowel syndrome) in children it was showed that intestinal dysbiosis can be both one of the causes of IBS and chronic colitis development and its effects.
Key words: children, intestinal dysbiosis, chronic colitis, irritated bowel syndrome.
Babanina S. M., Babanina M. U.
Using of probiotic in complex treatment diseases of mucous membrane chyildren`s mouths.
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Summаry. The aim of achievement was to study clinical efficiency of preparation BioGaia for correction microbiotsinoz and immunological children`s status, who have acute herpetic stomatitis. 50 children were examined. Using preparation BioGaia was effective enough. The result of it was normalization microbiotsinoz of mouth cavity and the state of cellular and humoral immunity became better.
Key words: acute herpetic stomatitis, BioGaia, treatment.
Nechay A. F.
Using of valproates in treatment of patients with West syndrome.
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Summary. West syndrome is an epileptic encephalopathy of infancy, characterized by infantile spasms, hypsarrhythmia on EEG, psychomotor retardation.Infantile spasms are resistant to majority of antiepileptic drugs. Valproates are medication of choice in those children. Results of using valproates in 30 patients with West syndrome have been presented in the paper. 5 of them (16,6%) had had total remission of infantile spasms, in 16 (53,3%) frequency of seizures had reduced more then to 50%, 9 (30%) had been resistant. Valproates had appeared to be of higher efficacy in patients with idiopathic West syndrome and in patients with perinatal injury of the brain.
Key words: West syndrome, treatment, valproates.
Ovcharenko L. S., Shamray I. V., Redko І. І., Zhikharevа N. V., Doroshenko S. V.
Some neurotransmitters serum levels in children with central nervous system perinatal disorders, depending on the bronchitis inflammatory process severity.
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Summary. With a comprehensive assessment of neurogenic inflammation in children with recurrent bronchitis and central nervous system perinatal disorders has been established characteristic of adaptive autonomous mechanisms — normal content of substance P in the serum of intercurrent period and increase in acute bronchitis. Neuroimmune changes as the source and the jet during the acute bronchitis in children with recurrent bronchitis and central nervous system perinatal disorders indicate a significant increase in inflammatory processes and simultaneous neurotransmitter imbalance.
Key words: children, bronchitis, substance P, vasoactive intestinal peptide.
Ivanov D. D., Sergeychuk S. Yu.
Phytoneering and urinary tract infections in children: cystitis.
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Summary. Minutes of the treatment of the urinary system infections does not involve the use of herbal therapy, with the exception of the phytoneering preparation Kanefron H, which is recommended for appointment in a period of acute symptoms of cystitis, as well as to prevent its recurrence for all age groups. Phytopreparations made on the base of phytoneering, closest to the recommendations of evidence-based medicine.
Keywords: evidence-based medicine, phitopreparations, phytoneering, urinary system infections,Kanefron N.
Senatorova A. S., Pomazunovskaja E. P., Muratov G. R., Kryzhanovskaja E. N.
Influence of some factors of the environments on development and the state of health of children of early age.
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Summary. Improvement of methods of diagnostics of deviations of health of the children's population by studying of risk factors was the work purpose. It is spent clinic-laboratory inspection 101 the child. All children were to divide on 2 groups depending on presence atopic dermatitis; law of occurrence of displays of diseases depending on employment of mothers on manufacture also has been established. Features of formation of a somatic pathology at children under influence are established environments. The received results open additional possibility of preventive maintenance of formation of chronic diseases.
Key words: children, environment, a state of health, the industry.
Velychko V. I.
Tне motivational training children of primary school age in the school weight management.
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Summary. Treatment of obesity should begin with the creation and/or increased motivation to reduce the patient's body weight. In trained us sick children in the school weight management skills were self-generated: daily measurement of body weight, blood pressure, keeping food diaries and conscious of child recommendations. Motivational program in school weight management is highly informative efficiency and its application in the treatment of obesity in children of primary school age helping to change the stereotype of child nutrition, which is the key to success not only weight loss but also long-term conservation achieved in the treatment results.
Key words: children of primary school age, obesity, motivational training, school weight management.
Kaladze N. N., Karmazina I. V., Meltseva E. M.
Rehabilitation of immune system in children with oncopathology taking into account the state of antioxidant status.
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Summary. Are investigated a condition of the peroxide oxidations of lipids (POL) and anti oxidant protection (АОP) at 178 children with haemoblastosis in remission and their change under influence of sanatorium rehabilitation. It is revealed, that at them activation of processes the POL and decrease of activity АОP takes place. Sanatorium rehabilitation salutarily influences a condition of processes the POL and АОP, reducing the phenomena disballans between the POL and АОP at this category of children.
Key word: haemoblastos, sanatorium rehabilitation, peroxide oxidations of lipids, anti oxidant protection.
«Детские» болезни: когда мы о них узнали?
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Кунсткамера.
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