• Сучасний метод посилення протизапальних, цитопротекторних та зволожувальних ефектів місцевої терапії алергічних ринитів у дітей
ua До змісту

Сучасний метод посилення протизапальних, цитопротекторних та зволожувальних ефектів місцевої терапії алергічних ринитів у дітей

SOVREMENNAYA PEDIATRIYA.2014.6(62):52–55; doi 10.15574/SP.2014.62.52

Сучасний метод посилення протизапальних, цитопротекторних та зволожувальних ефектів місцевої терапії алергічних ринитів у дітей

Овчаренко Л. С., Вертегел А. А., Андриенко Т. Г., Жихарева Н. В., Самохин И. В., Ткаченко В. Ю. 
ДУ «Запорізька медична академія післядипломної освіти МОЗ України»

Резюме. Показано терапевтичні можливості іригаційної терапії із застосуванням інноваційних технологій у лікуванні алергічних ринітів у дітей.

Ключові слова: діти, риніт, лікування, профілактика, ектоїн.

Література: 
1. Schwibbert K, Marin-Sanguino A, Bagyan I et al. 2011. A blueprint of ectoine metabolism from the genome of the industrial producer Halomonas elongata DSM 2581T. Environmental Microbiology. 13(8): 1973—1994. http://dx.doi.org/10.1111/j.1462-2920.2010.02336.x; PMid:20849449 PMCid:PMC3187862

2. Wald ER, Applegate KE, Bordley C et al. 2013. American Academy of Pediatrics: Clinical practice guideline for the diagnosis and management of acute bacterial sinusitis in children aged 1 to 18 years. Pediatrics. 132. 262—280.

3. Widderich N, Hoppner A, Pittelkow M et al. 2014, Apr. Biochemical Properties of Ectoine Hydroxylases from Extremophiles and Their Wider Taxonomic Distribution among Microorganisms. 9(4): 93809.

4. Chen JR, Jin L, Li XY. 2014. The effectiveness of nasal saline irrigation (seawater) in treatment of allergic rhinitis in children. Int J Pediatr Otorhinolaryngol. 78(7): 1115—8. http://dx.doi.org/10.1016/j.ijporl.2014.04.026; PMid:24809770

5. Chirico GI, Beccagutti F. 2010. Nasal obstruction in neonates and infants. Minerva Pediatr. 62(5): 499—505.

6. Saum SH, Pfeiffer F, Palm P et al. 2013. Chloride and organic osmolytes: a hybrid strategy to cope with elevated salinities by the moderately halophilic, chloride-dependent bacterium Halobacillus halophilus. Environ Microbiol. 15(5): 1619—33. http://dx.doi.org/10.1111/j.1462-2920.2012.02770.x; PMid:22583374

7. Cohen NA. 2006. Sinonasal mucociliary clearance in health and disease. Ann Otol Rhinol Laryngol. 196: 20—26.

8. Hong SD, Kim JH, Kim HY et al. 2014. Compliance and efficacy of saline irrigation in pediatric chronic rhinosinusitis. Auris Nasus Larynx. 41(1): 46—9. http://dx.doi.org/10.1016/j.anl.2013.07.008; PMid:23932052

9. Reshetnikov AS, Khmelenina VN, Mustakhimov II et al. 2011. Diversity and phylogeny of the ectoine biosynthesis genes in aerobic, moderately halophilic methylotrophic bacteria. Extremophiles. 15(6): 653—63. http://dx.doi.org/10.1007/s00792-011-0396-x; PMid:21971967

10. Dunn JD, Dion GR, McMains KC. 2013. Efficacy of nasal irrigations and nebulizations for nasal symptom relief. Curr Opin Otolaryngol. Head Neck Surg. 21: 248—251.

11. Buommino E, Schiraldi Ch, Baroni A et al. 2005. Ectoine from halophilic microorganisms induces the expression of hsp70 and hsp70B9 in human keratinocytes modulating the proinflammatory response. Cell Stress & Chaperones. 10(3): 197—203. http://dx.doi.org/10.1379/CSC-101R.1; PMCid:PMC1226017

12. Wang YH, Ku MS, Sun HL, Lue KH. 2014. Efficacy of nasal irrigation in the treatment of acute sinusitis in atopic children. J Microbiol. Immunol. Infect. 47(1): 63—9.

13. Wang YH, Yang CP, Ku MS et al. 2009. Efficacy of nasal irrigation in the treatment of acute sinusitis in children. Int J Pediatr Otorhinolaryngol. 73: 1696—1701.

14. Esposito S, Principi N. 2008. Italian Society of Pediatrics, Italian Society of Pediatric Infectivology, Italian Society of Pediatric Allergology and Immunology, Italian Society of Pediatric Respiratory Diseases, Italian Society of Preventive and Social Pediatrics; Italian Society of Otorhinolaryngology, Italian Society of Chemotherapy; Italian Society of Microbiology: Guidelines for the diagnosis and treatment of acute and subacute rhinosinusitis in children. J Chemother. 20: 147-157.

15. Prabhu J, Schauwecker F, Grammel N et al. 2004. Functional Expression of the Ectoine Hydroxylase Gene (thpD) from Streptomyces chrysomallus in Halomonas elongata. Applied And Environmental Microbiology. 70;5: 3130—3132.

16. Marchisio P, Varricchio A, Baggi E et al. 2012. Hypertonic saline in more effective than normal saline in seasonal allergic rhinitis in children. Int J Immunopathol Pharmacol. 25: 721—730.

17. Jeffe JS, Bhushan B, Schroeder JWJr. 2012. Nasal saline irrigation in children: a study of compliance and tolerance. Int J Pediatr Otorhinolaryngol. 76(3): 409-13. http://dx.doi.org/10.1016/j.ijporl.2011.12.022; PMid:22266167

18. Kassel JC, King D, Spurling GK. 2010. Saline nasal irrigation for acute upper respiratory tract infections. Cochrane Database Syst Rev. 17(3): CD006821.

19. Pflughoeft KJ, Kierek K, Watnick PI. 2003. Role of Ectoine in Vibrio cholerae Osmoadaptation. Applied And Environmental Microbiology. 69;10: 5919—5927.

20. Khianey R, Oppenheimer J. 2012. Is nasal saline irrigation all it is cracked up to be? Ann Allergy Asthma Immunol. 109: 20—28.

21. Mattos JL, Woodard CR, Payne SC. 2011. Trends in common rhinologic illnesses: analysis of U.S. healthcare surveys 1995—2007. Int Forum Allergy Rhinol. 1(1): 3—12. http://dx.doi.org/10.1002/alr.20003; PMid:22287302

22. Hildenbrand T, Weber R, Heubach C, Mosges R. 2011. Nasal douching in acute rhinosinusitis. Laryngorhinootologie. 90(6): 346—51.

23. Hermelingmeier KE, Weber RK, Hellmich M et al. 2012. Nasal irrigation as an adjunctive treatment in allergic rhinitis: a systematic review and meta-analysis. Am J Rhinol Allergy. 26: 119—125.

24. Marchisio P, Picca M, Torretta S et al. 2014. Nasal saline irrigation in preschool children: a survey of attitudes and prescribing habits of primary care pediatricians workingin northern Italy. Italian Journal of Pediatrics. 40: 47.

25. Oren A. 2010. Industrial and environmental applications of halophilic microorganisms. Environ Technol. 31(8—9): 825—34.

26. Pham V, Sykes K, Wei J. 2014. Long-term outcome of once daily nasal irrigation for the treatment of pediatric chronic rhinosinusitis. Laryngoscope. 124: 1000—1007.

27. Wei YH, Yuan FW, Chen WC, Chen SY. 2011. Production and characterization of ectoine by Marinococcus sp. ECT1 isolated from a high_salinity environment. J Biosci Bioeng. 111(3): 336—42.

28. Pastor JM, Bernal V, Salvador M et al. 2013. Role of Central Metabolism in the Osmoadaptation of the Halophilic Bacterium Chromohalobacter salexigens. J Biol Chem. 288(24): 17769—17781.

29. Wei JL, Sykes KJ, Johnson P et al. 2011. Safety and efficacy of once_daily nasal irrigation for the treatment of pediatric chronic rhinosinusitis. Laryngoscope. 121(9): 1989—2000.

30. Bursy J, Kuhlmann AU, Pittelkow M et al. 2008. Synthesis and Uptake of the Compatible Solutes Ectoine and 5-Hydroxyectoine by Streptomyces coelicolor A3(2) in Response to Salt and Heat Stresses. Applied And Environmental Microbiology. 74;23: 7286—7296.

31. Rabago D, Zgierska A, Peppard P, Bamber A. 2009. The prescribing patterns of Wisconsin family physicians surrounding saline nasal irrigation for upper respiratory conditions. WMJ. 108: 145—150.