HEALTH OF WOMAN.2015.10(106):20–22 

Клинические аспекты долгосрочной терапии эндометриоза диеногестом 

Пирогова В. И., Шурпяк С. А., Кривко Б. Я.                       

Львовский национальный медицинский университет имени Данила Галицкого

Львовская городская больница скорой медицинской помощи 

В статье рассматриваются клинические аспекты долгосрочной терапии генитального эндометриоза с применением диеногеста у пациенток с гинекологическим пролиферативным синдромом. 

Ключевые слова: эндометриоз, диеногест, гинекологический пролиферативный синдром. 

Литература:

1. ESRHE guideline. http://guidelines.endometriosis. org/pain.html. 2007.

2. Giudice LC. 2010. Endometriosis. N Engl J Med 362:2389–98. http://dx.doi.org/10.1056/NEJMcp1000274; PMid:20573927 PMCid:PMC3108065

3. Guo SW. 2009. Recurrence of endometriosis and its control. Hum Reprod Updare 15:441–61. http://dx.doi.org/10.1093/humupd/dmp007; PMid:19279046

4. Harada T, Momoeda M, Taketani Y et al. 2009. Dienogest is as effective as intranasal buserelin acetate for the relief of pain symptoms associated with endometriosis – a randomized, double-blind, multicenter, controlled trial. Fertil Steril. 91(3):675–681. http://dx.doi.org/10.1016/j.fertnstert.2007.12.080; PMid:18653184

5. Hughes E, Brown J, Collins JJ, Farquhar C, Fedorkow DM, Vandekerckhove P. 2007, Jul 18. Ovulation suppression for endometriosis. Cochrane Database Syst Rev 3:CD000155. PMid:17636607

6. Klipping C, Duijkers I, Faustmann TA et al. 2010. Pharmacodynamic study of four oral dosages of dienogest. Fertil Steril 94(suppl):S181. http://dx.doi.org/10.1016/j.fertnstert.2010.07.708

7. Leyland N, Casper R, Laberge Ph, Singh SS et al. 2010. Endometriosis: diagnosis and management. SOGC Clinical and practical guideline. Journal of Obstetrics and Gynaecology Canada 32(7):1–28. http://dx.doi.org/10.1016/S1701-2163(16)34589-3

8. Management of endometriosis. Practical Bulletin No.114. The American College of Obstetricians and Gynecologists. Obstet Gynecol 116:223–36. 2010. http://dx.doi.org/10.1097/AOG.0b013e3181e8b073; PMid:20567196

9. McCormack PL. 2010. Dienogest: a review of its use in the treatment of endometriosis. Drugs 70(16):2073–88. http://dx.doi.org/10.2165/11206320-000000000-00000; PMid:20964453

10. Momoeda M, Harada T, Terakawa N et al. 2009. Long-term use of dienogest for the treatment of endometriosis. J Obstet Gynaecol Res. 35(6):1069–1076. http://dx.doi.org/10.1111/j.1447-0756.2009.01076.x; PMid:20025633

11. Momoeda M, Taketani Y. 2007. Randomized double-blind, multicentre, parallel-group dose–response study of dienogest in patients with endometriosis. Jpn Pharmacol Ther. 35:769–783.

12. Petraglia F, Hornung D, Seitz C et al. 2011. Reduced pelvic pain in women with endometriosis: efficacy of long-term dienogest treatment. Arch Gynecol Obstet. 285(1):167–173. http://dx.doi.org/10.1007/s00404-011-1941-7; PMid:21681516 PMCid:PMC3249203

13. Sasagawa S, Shimizu Y, Kami H, Takeuchi T, Mita S, Imada K et al. 2008. Dienogest is a selective progesterone receptor agonist in transactivation analysis with potent oral endometrial activity due to its efficient pharmacokinetic profile. Steroids 73:222–231. http://dx.doi.org/10.1016/j.steroids.2007.10.003; PMid:18061638

14. Strowitzki T, Faustmann T, Gerlinger C et al. 2010. Dienogest in the treatment of endometriosis-associated pelvic pain: a 12-week, randomized, double-blind, placebo-controlled study. Eur J Obstet Gynecol Reprod Biol. 151:193–198. http://dx.doi.org/10.1016/j.ejogrb.2010.04.002; PMid:20444534

15. Strowitzki T, Marr J, Gerlinger C, Faustmann T, Seitz C. 2010. Dienogest is as effective as leuprolide acetate in treating the painful symptoms of endometriosis: A 24-week, randomized, multicentre, open-label trial. Hum Reprod. 25(3):633–641. http://dx.doi.org/10.1093/humrep/dep469; PMid:20089522