Modern Pediatrics. Ukraine. 5(109): 45-51. doi 10.15574/SP.2020.109.45
Рейтмаер М. И., Волосянко А. Б., Синоверська О. Б., Иванишин Л. Я., Алексеева Ю. И.
Ивано—Франковский национальный медицинский университет, Украина

Для цитирования: Рейтмаер МИ, Волосянко АБ, Синоверська ОБ, Иванишин ЛЯ, Алексеева ЮИ. (2020). Дебют и течение редкого ювенильного дерматомиозита. Часть ІІ: клинический анализ со сравнительно-аналитическим обзором литературы. Современная педиатрия. Украина. 5(109): 45—51. doi 10.15574/SP.2020.109.45.
Статья поступила в редакцию 13.01.2020 г., принята в печать 29.05.2020 г.

В первой части статьи описан редкий случай дебюта и течения ювенильного дерматомиозита. Во второй части выполнен сравнительно-клинический анализ результатов собственного наблюдения с другими аналогичными сообщениями.
Основное внимание сосредоточено на атипичных вариантах начала заболевания, в частности признаках выраженного интоксикационного синдрома, геморрагически-некротической сыпи, анасарки, поражения ротовой полости в виде стоматита и язвенно-некротического глоссита. Показано трудности ранней диагностики болезни на фоне отсроченной манифестации патогномоничных кожных проявлений и отсутствии достоверных признаков миопатического синдрома. Обозначены клинико-лабораторные особенности амиопатического ювенильного дерматомиозита с устойчивым поражением кожи. Представлены три дифференцированных плана-рекомендации специалистов Североамериканского альянса детского артрита и ревматологических исследований в педиатрии по лечению больных без поражения мышечной ткани и тех, у кого клинические проявления миопатии наблюдались только в первые месяцы болезни. Прослежены современные тенденции достижений и пробелов в классификации, диагностике и лечении различных форм ювенильного дерматомиозита. На основе обзора и анализа научных публикаций освещены возможные прогностические последствия амиопатической формы этого заболевания у детей.
Исследование было выполнено в соответствии с принципами Хельсинкской Декларации. Протокол исследования был одобрен Локальным этическим комитетом учреждения. На проведение исследований было получено информированное согласие родителей, ребёнка.
Авторы заявляют об отсутствии конфликта интересов.
Ключевые слова: ювенильный дерматомиозит, ювенильный амиопатический дерматомиозит, атипичное течение, язвенно-некротический глоссит, анасарка, псориаз, лечение.

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