HEALTH OF WOMAN. 2016.8(114):37–40; doi 10.15574/HW.2016.114.37 
 

Innovative approaches to the correction of chronotrope status of pregnant and lactating women

Zhuk S. I., Bondarenko K. K.

National Medical Academy of Postgraduate Education P. L. Shupyk, Kiev

Most recent studies show the impact of violations in the metabolism of folate and metin period in the pathogenesis of neural tube defects (NTD) of the fetus. Metafolin has a number of advantages, which primarily includes direct intake of substances in biologically active form and the optimum effect, even in the case when the patient homozygote and/or heterozygote genotype 677С T polymorphism in MTHFR. With the aim of prevention and treatment of various pathological conditions related to folate deficiency during pregnancy, it is advisable to apply vitamin-mineral complexes, containing metafolin – active form of folate with high bioavailability.

Key words: MTHFR, metafolin, folic acid, pregnancy.

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