• Use of herbal dopamine mimetics in adolescents and young women with menstrual irregularities

Use of herbal dopamine mimetics in adolescents and young women with menstrual irregularities

HEALTH OF WOMAN. 2018.4(130):52–58

Kuznetsova I. V., Uspenskaya Yu. B., DiL V. V., Grineva A. M.
SIC HBOU HPE The first Moscow State Medical University ІM. Sechenova, Russia
Published: Obstetrics and Gynecology, 2015, No. 10.

Functional impairments of the menstrual cycle constitute a significant proportion in the pattern of gynecological diseases in adolescents and young women. Non-hormonal correction is one of the leading therapies of these impairments.

The objective: to evaluate the efficiency of using a Vitex agnus-castus-containing drug in adolescents and young women with menstrual irregularities.

Materials and methods. The open-label randomized comparative trial enrolled 80 adolescents and young women with functional impairments of the menstrual cycle who were randomized into two groups receiving Cyclodynon® (a study group) or a multivitamin complex (a control group) for 6 months.

Results. The use of Cyclodynon® was found to shorten intermenstrual intervals and to improve acyclic bleeding control in patients with oligomenorrhea, to significantly reduce the degree of mastalgia, to improve autonomic function, and to normalize prolactin secretion.

Conclusion. The administration of Cyclodynon® may be regarded as a therapy option in patients with functional menstrual cycle impairments presumptively associated with disorders of prolactin secretion.

Key words: hyperprolactinemia, oligomenorrhea, amenorrhea, hypothalamic dysfunction, anovulation, mastalgia, Vitex agnus-castus, Cyclodynon®.


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